Cargando…

Phosphorylation-dependent regulation of the NOTCH1 intracellular domain by dual-specificity tyrosine-regulated kinase 2

NOTCH proteins constitute a receptor family with a widely conserved role in cell cycle, growing and development regulation. NOTCH1, the best characterised member of this family, regulates the expression of key genes in cell growth and angiogenesis, playing an essential role in cancer development. Th...

Descripción completa

Detalles Bibliográficos
Autores principales: Morrugares, Rosario, Correa-Sáez, Alejandro, Moreno, Rita, Garrido-Rodríguez, Martín, Muñoz, Eduardo, de la Vega, Laureano, Calzado, Marco A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320039/
https://www.ncbi.nlm.nih.gov/pubmed/31605148
http://dx.doi.org/10.1007/s00018-019-03309-9