Compromised Hippocampal Neuroplasticity in the Interferon-α and Toll-like Receptor-3 Activation-Induced Mouse Depression Model

Disrupted neuronal plasticity due to subtle inflammation is considered to play a fundamental role in the pathogenesis of major depressive disorder. Interferon-α (IFN-α) potentiates immune responses against viral pathogens that induce toll-like receptor-3 (TLR3) activation but evokes severe major dep...

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Detalles Bibliográficos
Autores principales: Sanchez-Mendoza, Eduardo H., Camblor-Perujo, Santiago, Martins Nascentes-Melo, Luiza, Dzyubenko, Egor, Fleischer, Michael, Silva de Carvalho, Tayana, Schmitt, Linda-Isabell, Leo, Markus, Hagenacker, Tim, Herring, Arne, Keyvani, Kathy, Bera, Sujoy, Kononenko, Natalia, Kleinschnitz, Christoph, Hermann, Dirk M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320059/
https://www.ncbi.nlm.nih.gov/pubmed/32504419
http://dx.doi.org/10.1007/s12035-020-01927-0

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