Cargando…

Thioredoxin System Protein Expression Is Associated with Poor Clinical Outcome in Adult and Paediatric Gliomas and Medulloblastomas

The thioredoxin (Trx) system is an important enzyme family that regulates cellular redox homeostasis. Protein expression of Trx system family members has been assessed in various cancers and linked to various clinicopathological variables, disease progression, treatment response and survival outcome...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yao, Anqi, Storr, Sarah J., Al-hadyan, Khaled, Rahman, Ruman, Smith, Stuart, Grundy, Richard, Paine, Simon, Martin, Stewart G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320063/ https://www.ncbi.nlm.nih.gov/pubmed/32418115 http://dx.doi.org/10.1007/s12035-020-01928-z

Ejemplares similares

Antiangiogenic Therapy and Mechanisms of Tumor Resistance in Malignant Glioma
por: Rahman, Ruman, et al.
Publicado: (2010)

Cytotoxic and Radiosensitising Effects of a Novel Thioredoxin Reductase Inhibitor in Brain Cancers
por: Yao, Anqi, et al.
Publicado: (2022)

Endothelial-like malignant glioma cells in dynamic three dimensional culture identifies a role for VEGF and FGFR in a tumor-derived angiogenic response
por: Smith, Stuart J., et al.
Publicado: (2015)

HGG-48. A comparative proteomic analysis of the cell membrane of histone 3 mutated paediatric high-grade gliomas in order to identify potential immunotherapeutic targets
por: Suresh, Sneha, et al.
Publicado: (2022)

The Molecular and Phenotypic Basis of the Glioma Invasive Perivascular Niche
por: Diksin, Mohammed, et al.
Publicado: (2017)

microRNA network analysis identifies miR-29 cluster as key regulator of LAMA2 in ependymoma
por: Lourdusamy, Anbarasu, et al.
Publicado: (2015)

Cytotoxic and radiosensitising effects of a novel thioredoxin reductase inhibitor in breast cancer
por: Abdullah, Nurul A, et al.
Publicado: (2021)

EPEN-05. Adenosine receptor expression in paediatric ependymoma
por: Spanoudakis, Chelsea, et al.
Publicado: (2022)

PAEDIATRIC-01 SURGICAL OUTCOME OF MEDULLOBLASTOMA IN ETHIOPIA
por: Akililu, Yemisirach Bizuneh, et al.
Publicado: (2023)

CLRM-08. TRIAL WORKING GROUPS FOR PAEDIATRIC BRAIN TUMOURS
por: Rahman, Ruman, et al.
Publicado: (2021)

EPCT-08. TRIAL WORKING GROUPS FOR PAEDIATRIC BRAIN TUMOURS
por: Rahman, Ruman, et al.
Publicado: (2021)

CD105 (Endoglin) exerts prognostic effects via its role in the microvascular niche of paediatric high grade glioma
por: Smith, Stuart J., et al.
Publicado: (2012)

EPEN-43. TARGETING INTRA-TUMOUR HETEROGENEITY IN PAEDIATRIC EPENDYMOMA: AN INTEGRATED OMICS STUDY TOWARDS PATIENT-TAILORED THERAPY
por: Pandele, Alina, et al.
Publicado: (2020)

Expression alterations define unique molecular characteristics of spinal ependymomas
por: Lourdusamy, Anbarasu, et al.
Publicado: (2015)

Thioredoxin Confers Intrinsic Resistance to Cytostatic Drugs in Human Glioma Cells
por: Haas, Bodo, et al.
Publicado: (2018)

IMG-01. DWI RATIO OF HISTOLOGICAL MOLECULAR SUBTYPES OF PAEDIATRIC MEDULLOBLASTOMAS
por: Tang, Phua Hwee, et al.
Publicado: (2020)

Pediatric glioma and medulloblastoma risk and population demographics: a Poisson regression analysis
por: Muskens, Ivo S, et al.
Publicado: (2020)

Low-Density Lipoprotein Pathway Is a Ubiquitous Metabolic Vulnerability in High Grade Glioma Amenable for Nanotherapeutic Delivery
por: Adekeye, Adenike O., et al.
Publicado: (2023)

Thioredoxin Reductase Inhibitors as Potential Antitumors: Mercury Compounds Efficacy in Glioma Cells
por: Pires, Vanessa, et al.
Publicado: (2022)

The Molecular Landscape of Medulloblastoma in Teenagers and Young Adults
por: Mohammed, Omar J., et al.
Publicado: (2022)

MEDB-23. Targeting epigenetic dysregulation in medulloblastoma with poor prognosis
por: Badodi, Sara, et al.
Publicado: (2022)

Expression of Syk and MAP4 proteins in ovarian cancer
por: Zhang, Siwei, et al.
Publicado: (2019)

Lipoprotein Deprivation Reveals a Cholesterol-Dependent Therapeutic Vulnerability in Diffuse Glioma Metabolism
por: Wood, James, et al.
Publicado: (2022)

HGG-38. A COMPARATIVE PROTEOMIC-ANALYSIS OF THE CELL MEMBRANE FRACTIONS OF HISTONE 3 MUTATED BRAIN TUMOURS TO IDENTIFY NOVEL THERAPEUTICS
por: Pickering, James, et al.
Publicado: (2020)

High Thioredoxin Domain-Containing Protein 11 Expression Is Associated with Tumour Progression in Glioma
por: Chen, Ying-Tso, et al.
Publicado: (2023)

The impact of magnetic resonance imaging spectroscopy parameters on differentiating between paediatric medulloblastoma and ependymoma
por: Duc, Nguyen Minh
Publicado: (2021)

Tissue metabolite profiles for the characterisation of paediatric cerebellar tumours
por: Bennett, Christopher D., et al.
Publicado: (2018)

ID3 contributes to cerebrospinal fluid seeding and poor prognosis in medulloblastoma
por: Phi, Ji Hoon, et al.
Publicado: (2013)

TOP2A correlates with poor prognosis and affects radioresistance of medulloblastoma
por: Zhang, Yufeng, et al.
Publicado: (2022)

The structural basis for the negative regulation of thioredoxin by thioredoxin-interacting protein
por: Hwang, Jungwon, et al.
Publicado: (2014)

Thioredoxin Profiling of Multiple Thioredoxin-Like Proteins in Staphylococcus aureus
por: Peng, Hui, et al.
Publicado: (2018)

BLBP Is Both a Marker for Poor Prognosis and a Potential Therapeutic Target in Paediatric Ependymoma
por: Sabnis, Durgagauri H., et al.
Publicado: (2021)

Spatially resolved transcriptomic profiles reveal unique defining molecular features of infiltrative 5ALA-metabolizing cells associated with glioblastoma recurrence
por: Andrieux, Geoffroy, et al.
Publicado: (2023)

Overcoming multiple drug resistance mechanisms in medulloblastoma
por: Othman, Ramadhan T, et al.
Publicado: (2014)

PARP inhibition sensitizes childhood high grade glioma, medulloblastoma and ependymoma to radiation
por: van Vuurden, Dannis G., et al.
Publicado: (2011)

The Role of Apparent Diffusion Coefficient in the Differentiation between Cerebellar Medulloblastoma and Brainstem Glioma
por: Minh Thong, Pham, et al.
Publicado: (2020)

A novel indication of thioredoxin-interacting protein as a tumor suppressor gene in malignant glioma
por: Zhang, Pengxing, et al.
Publicado: (2017)

The prognostic role of intragenic copy number breakpoints and identification of novel fusion genes in paediatric high grade glioma
por: Carvalho, Diana, et al.
Publicado: (2014)

Thioredoxin interacting protein and its association with clinical outcome in gastro-oesophageal adenocarcinoma()
por: Woolston, Caroline M., et al.
Publicado: (2013)

Combination of Ribociclib and Gemcitabine for the Treatment of Medulloblastoma
por: Pribnow, Allison, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_a502a0l071sapn60he71epatfn