ESCRT-III-associated proteins and spastin inhibit protrudin-dependent polarised membrane traffic

Mutations in the gene encoding the microtubule severing ATPase spastin are the most frequent cause of hereditary spastic paraplegia, a genetic condition characterised by length-dependent axonal degeneration. Here, we show that HeLa cells lacking spastin and embryonic fibroblasts from a spastin knock...

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Detalles Bibliográficos
Autores principales: Connell, James W., Allison, Rachel J., Rodger, Catherine E., Pearson, Guy, Zlamalova, Eliska, Reid, Evan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320071/
https://www.ncbi.nlm.nih.gov/pubmed/31587092
http://dx.doi.org/10.1007/s00018-019-03313-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320071/
https://www.ncbi.nlm.nih.gov/pubmed/31587092
http://dx.doi.org/10.1007/s00018-019-03313-z

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