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ESCRT-III-associated proteins and spastin inhibit protrudin-dependent polarised membrane traffic
Mutations in the gene encoding the microtubule severing ATPase spastin are the most frequent cause of hereditary spastic paraplegia, a genetic condition characterised by length-dependent axonal degeneration. Here, we show that HeLa cells lacking spastin and embryonic fibroblasts from a spastin knock...
Autores principales: | Connell, James W., Allison, Rachel J., Rodger, Catherine E., Pearson, Guy, Zlamalova, Eliska, Reid, Evan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320071/ https://www.ncbi.nlm.nih.gov/pubmed/31587092 http://dx.doi.org/10.1007/s00018-019-03313-z |
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