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Substrate Channeling via a Transient Protein-Protein Complex: The case of D-Glyceraldehyde-3-Phosphate Dehydrogenase and L-Lactate Dehydrogenase

Substrate channeling studies have frequently failed to provide conclusive results due to poor understanding of this subtle phenomenon. We analyzed the mechanism of NADH-channeling from D-glyceraldehyde-3-phosphate dehydrogenase (GAPDH) to L-lactate Dehydrogenase (LDH) using enzymes from different ce...

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Detalles Bibliográficos
Autores principales: Svedružić, Željko M., Odorčić, Ivica, Chang, Christopher H., Svedružić, Draženka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320145/
https://www.ncbi.nlm.nih.gov/pubmed/32591631
http://dx.doi.org/10.1038/s41598-020-67079-2