Cargando…

Substrate Channeling via a Transient Protein-Protein Complex: The case of D-Glyceraldehyde-3-Phosphate Dehydrogenase and L-Lactate Dehydrogenase

Substrate channeling studies have frequently failed to provide conclusive results due to poor understanding of this subtle phenomenon. We analyzed the mechanism of NADH-channeling from D-glyceraldehyde-3-phosphate dehydrogenase (GAPDH) to L-lactate Dehydrogenase (LDH) using enzymes from different ce...

Descripción completa

Detalles Bibliográficos
Autores principales:	Svedružić, Željko M., Odorčić, Ivica, Chang, Christopher H., Svedružić, Draženka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320145/ https://www.ncbi.nlm.nih.gov/pubmed/32591631 http://dx.doi.org/10.1038/s41598-020-67079-2

Ejemplares similares

In silico design of the first DNA-independent mechanism-based inhibitor of mammalian DNA methyltransferase Dnmt1
por: Miletić, Vedran, et al.
Publicado: (2017)

THE HISTOCHEMICAL DEMONSTRATION OF GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE ACTIVITY
por: Himmelhoch, S. Ralph, et al.
Publicado: (1961)

Glyceraldehyde-3-Phosphate Dehydrogenase of Babesia microti Is a Plasminogen- and Actin-Binding Protein
por: Liu, Xiangye, et al.
Publicado: (2019)

THE INHIBITION OF d-GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE BY SPECIFIC ANTISERUM
por: Krebs, Edwin G., et al.
Publicado: (1948)

Testis-specific glyceraldehyde-3-phosphate dehydrogenase: origin and evolution
por: Kuravsky, Mikhail L, et al.
Publicado: (2011)

Functional consequences of piceatannol binding to glyceraldehyde-3-phosphate dehydrogenase
por: Gerszon, Joanna, et al.
Publicado: (2018)

Glyceraldehyde-3-phosphate Dehydrogenase Is a Multifaceted Therapeutic Target
por: Lazarev, Vladimir F., et al.
Publicado: (2020)

TKTL1 Knockdown Impairs Hypoxia-Induced Glucose-6-phosphate Dehydrogenase and Glyceraldehyde-3-phosphate Dehydrogenase Overexpression
por: Baptista, Inês, et al.
Publicado: (2022)

Characterization and possible function of glyceraldehyde-3-phosphate dehydrogenase-spermatogenic protein GAPDHS in mammalian sperm
por: Margaryan, Hasmik, et al.
Publicado: (2015)

Role of Glyceraldehyde 3-Phosphate Dehydrogenase in the Development and Progression of Diabetic Retinopathy
por: Kanwar, Mamta, et al.
Publicado: (2009)

A cryoprotectant induces conformational change in glyceraldehyde-3-phosphate dehydrogenase
por: Kim, Yong Ju
Publicado: (2018)

Sperm glyceraldehyde 3-phosphate dehydrogenase gene expression in asthenozoospermic spermatozoa
por: Paoli, Donatella, et al.
Publicado: (2017)

Cytosolic Glyceraldehyde-3-Phosphate Dehydrogenase Is Phosphorylated during Seed Development
por: Piattoni, Claudia V., et al.
Publicado: (2017)

Aberrant Expression of Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) in Warthin Tumors
por: Mandic, Robert, et al.
Publicado: (2020)

Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase enhances formation of the blood-clot lysis protein plasmin
por: Pirovich, David B., et al.
Publicado: (2020)

A mutation in glyceraldehyde 3-phosphate dehydrogenase alters endocytosis in CHO cells
Publicado: (1995)

Glyceraldehyde-3-Phosphate Dehydrogenase Acts as a Mitochondrial Trans-S-Nitrosylase in the Heart
por: Kohr, Mark J., et al.
Publicado: (2014)

The Plastidial Glyceraldehyde-3-Phosphate Dehydrogenase Is Critical for Abiotic Stress Response in Wheat
por: Li, Xixi, et al.
Publicado: (2019)

Interactome of Glyceraldehyde-3-Phosphate Dehydrogenase Points to the Existence of Metabolons in Paracoccidioides lutzii
por: e Silva, Kleber Santiago Freitas, et al.
Publicado: (2019)

Antimicrobial silver targets glyceraldehyde-3-phosphate dehydrogenase in glycolysis of E. coli
por: Wang, Haibo, et al.
Publicado: (2019)

Diverse Localization and Protein Binding Abilities of Glyceraldehyde-3-Phosphate Dehydrogenase in Pathogenic Bacteria: The Key to its Multifunctionality?
por: Kopeckova, Monika, et al.
Publicado: (2020)

A role for glyceraldehyde-3-phosphate dehydrogenase in the development of thermotolerance in Xenopus laevis embryos
Publicado: (1988)

The Glyceraldehyde-3-Phosphate Dehydrogenase and the Small GTPase Rab 2 Are Crucial for Brucella Replication
por: Fugier, Emilie, et al.
Publicado: (2009)

Glyceraldehyde-3-Phosphate Dehydrogenase: A Promising Target for Molecular Therapy in Hepatocellular Carcinoma
por: Ganapathy-Kanniappan, Shanmugasundaram, et al.
Publicado: (2012)

Pattern Recognition Techniques Applied to the Study of Leishmanial Glyceraldehyde-3-Phosphate Dehydrogenase Inhibition
por: Lozano, Norka B. H., et al.
Publicado: (2014)

Glyceraldehyde 3-Phosphate Dehydrogenase-Telomere Association Correlates with Redox Status in Trypanosoma cruzi
por: Pariona-Llanos, Ricardo, et al.
Publicado: (2015)

Tyr‐Asp inhibition of glyceraldehyde 3‐phosphate dehydrogenase affects plant redox metabolism
por: Moreno, Juan C, et al.
Publicado: (2021)

Thermal stability and structure of glyceraldehyde-3-phosphate dehydrogenase from the coral Acropora millepora
por: Perez, Astrid M., et al.
Publicado: (2021)

Crystal Structures of Group B Streptococcus Glyceraldehyde-3-Phosphate Dehydrogenase: Apo-Form, Binary and Ternary Complexes
por: Schormann, Norbert, et al.
Publicado: (2016)

A major surface protein on group A streptococci is a glyceraldehyde-3- phosphate-dehydrogenase with multiple binding activity
Publicado: (1992)

The glyceraldehyde-3-phosphate dehydrogenase GapDH of Corynebacterium diphtheriae is redox-controlled by protein S-mycothiolation under oxidative stress
por: Hillion, Melanie, et al.
Publicado: (2017)

Identification of Bacterial Protein Interaction Partners Points to New Intracellular Functions of Francisella tularensis Glyceraldehyde-3-Phosphate Dehydrogenase
por: Kopeckova, Monika, et al.
Publicado: (2020)

AMP-activated protein kinase-dependent nuclear localization of glyceraldehyde 3-phosphate dehydrogenase in senescent human diploid fibroblasts
por: Sohn, Jee Young, et al.
Publicado: (2022)

Regulation of Intersubunit Interactions in Homotetramer of Glyceraldehyde-3-Phosphate Dehydrogenases upon Its Immobilization in Protein—Kappa-Carrageenan Gels
por: Makshakova, Olga, et al.
Publicado: (2023)

Improved Production of 2,3-Butanediol in Bacillus amyloliquefaciens by Over-Expression of Glyceraldehyde-3-Phosphate Dehydrogenase and 2,3-butanediol Dehydrogenase
por: Yang, Taowei, et al.
Publicado: (2013)

Posttranscriptional regulation of angiotensin II type 1 receptor expression by glyceraldehyde 3-phosphate dehydrogenase
por: Backlund, Michael, et al.
Publicado: (2009)

Glyceraldehyde-3-Phosphate Dehydrogenase Interacts with Proapoptotic Kinase Mst1 to Promote Cardiomyocyte Apoptosis
por: You, Bei, et al.
Publicado: (2013)

Identification of Glyceraldehyde 3-Phosphate Dehydrogenase Sequence and Expression Profiles in Tree Shrew (Tupaia belangeri)
por: Zheng, Yu, et al.
Publicado: (2014)

Glyceraldehyde 3-phosphate dehydrogenase negatively regulates human immunodeficiency virus type 1 infection
por: Kishimoto, Naoki, et al.
Publicado: (2012)

Mycobacterium tuberculosis Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Functions as a Receptor for Human Lactoferrin
por: Malhotra, Himanshu, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_o573mud66ehscf7a2ti7sv7mg4