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Fishing for newly synthesized proteins with phosphonate-handles

Bioorthogonal chemistry introduces affinity-labels into biomolecules with minimal disruption to the original system and is widely applicable in a range of contexts. In proteomics, immobilized metal affinity chromatography (IMAC) enables enrichment of phosphopeptides with extreme sensitivity and sele...

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Detalles Bibliográficos
Autores principales:	Kleinpenning, Fleur, Steigenberger, Barbara, Wu, Wei, Heck, Albert J. R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320153/ https://www.ncbi.nlm.nih.gov/pubmed/32591520 http://dx.doi.org/10.1038/s41467-020-17010-0

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