miR-181a initiates and perpetuates oncogenic transformation through the regulation of innate immune signaling

Genomic instability (GI) predisposes cells to malignant transformation, however the molecular mechanisms that allow for the propagation of cells with a high degree of genomic instability remain unclear. Here we report that miR-181a is able to transform fallopian tube secretory epithelial cells throu...

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Detalles Bibliográficos
Autores principales: Knarr, Matthew, Avelar, Rita A., Sekhar, Sreeja C., Kwiatkowski, Lily J., Dziubinski, Michele L., McAnulty, Jessica, Skala, Stephanie, Avril, Stefanie, Drapkin, Ronny, DiFeo, Analisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320168/
https://www.ncbi.nlm.nih.gov/pubmed/32591511
http://dx.doi.org/10.1038/s41467-020-17030-w

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