ESTRO/ACROP IORT recommendations for intraoperative radiation therapy in locally recurrent rectal cancer

Multimodal strategies have been implemented for locally recurrent rectal cancer scheduled for complete surgical resection. Irradiation and systemic therapy have been added to improve the oncological outcome, as surgery alone was associated with a poor prognosis. Intraoperative irradiation (IORT) is...

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Detalles Bibliográficos
Autores principales: Calvo, Felipe A., Sole, Claudio V., Rutten, Harm J., Dries, Wim J., Lozano, Miguel A., Cambeiro, Mauricio, Poortmans, Philip, González-Bayón, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320231/
https://www.ncbi.nlm.nih.gov/pubmed/32613091
http://dx.doi.org/10.1016/j.ctro.2020.06.007
Descripción
Sumario:Multimodal strategies have been implemented for locally recurrent rectal cancer scheduled for complete surgical resection. Irradiation and systemic therapy have been added to improve the oncological outcome, as surgery alone was associated with a poor prognosis. Intraoperative irradiation (IORT) is a component of irradiation intensification. Long-term cancer control and a higher survival rate were consistently reported in patients who had IORT as a component of their multidisciplinary treatment. The experience reported by expert IORT groups is reviewed and recommendations to guide clinical practice are explained in detail.

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