ESTRO/ACROP IORT recommendations for intraoperative radiation therapy in locally recurrent rectal cancer

Multimodal strategies have been implemented for locally recurrent rectal cancer scheduled for complete surgical resection. Irradiation and systemic therapy have been added to improve the oncological outcome, as surgery alone was associated with a poor prognosis. Intraoperative irradiation (IORT) is...

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Autores principales: Calvo, Felipe A., Sole, Claudio V., Rutten, Harm J., Dries, Wim J., Lozano, Miguel A., Cambeiro, Mauricio, Poortmans, Philip, González-Bayón, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320231/
https://www.ncbi.nlm.nih.gov/pubmed/32613091
http://dx.doi.org/10.1016/j.ctro.2020.06.007
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author Calvo, Felipe A.
Sole, Claudio V.
Rutten, Harm J.
Dries, Wim J.
Lozano, Miguel A.
Cambeiro, Mauricio
Poortmans, Philip
González-Bayón, Luis
author_facet Calvo, Felipe A.
Sole, Claudio V.
Rutten, Harm J.
Dries, Wim J.
Lozano, Miguel A.
Cambeiro, Mauricio
Poortmans, Philip
González-Bayón, Luis
author_sort Calvo, Felipe A.
collection PubMed
description Multimodal strategies have been implemented for locally recurrent rectal cancer scheduled for complete surgical resection. Irradiation and systemic therapy have been added to improve the oncological outcome, as surgery alone was associated with a poor prognosis. Intraoperative irradiation (IORT) is a component of irradiation intensification. Long-term cancer control and a higher survival rate were consistently reported in patients who had IORT as a component of their multidisciplinary treatment. The experience reported by expert IORT groups is reviewed and recommendations to guide clinical practice are explained in detail.
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spelling pubmed-73202312020-06-30 ESTRO/ACROP IORT recommendations for intraoperative radiation therapy in locally recurrent rectal cancer Calvo, Felipe A. Sole, Claudio V. Rutten, Harm J. Dries, Wim J. Lozano, Miguel A. Cambeiro, Mauricio Poortmans, Philip González-Bayón, Luis Clin Transl Radiat Oncol Article Multimodal strategies have been implemented for locally recurrent rectal cancer scheduled for complete surgical resection. Irradiation and systemic therapy have been added to improve the oncological outcome, as surgery alone was associated with a poor prognosis. Intraoperative irradiation (IORT) is a component of irradiation intensification. Long-term cancer control and a higher survival rate were consistently reported in patients who had IORT as a component of their multidisciplinary treatment. The experience reported by expert IORT groups is reviewed and recommendations to guide clinical practice are explained in detail. Elsevier 2020-06-17 /pmc/articles/PMC7320231/ /pubmed/32613091 http://dx.doi.org/10.1016/j.ctro.2020.06.007 Text en © 2020 Published by Elsevier B.V. on behalf of European Society for Radiotherapy and Oncology. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Calvo, Felipe A.
Sole, Claudio V.
Rutten, Harm J.
Dries, Wim J.
Lozano, Miguel A.
Cambeiro, Mauricio
Poortmans, Philip
González-Bayón, Luis
ESTRO/ACROP IORT recommendations for intraoperative radiation therapy in locally recurrent rectal cancer
title ESTRO/ACROP IORT recommendations for intraoperative radiation therapy in locally recurrent rectal cancer
title_full ESTRO/ACROP IORT recommendations for intraoperative radiation therapy in locally recurrent rectal cancer
title_fullStr ESTRO/ACROP IORT recommendations for intraoperative radiation therapy in locally recurrent rectal cancer
title_full_unstemmed ESTRO/ACROP IORT recommendations for intraoperative radiation therapy in locally recurrent rectal cancer
title_short ESTRO/ACROP IORT recommendations for intraoperative radiation therapy in locally recurrent rectal cancer
title_sort estro/acrop iort recommendations for intraoperative radiation therapy in locally recurrent rectal cancer
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320231/
https://www.ncbi.nlm.nih.gov/pubmed/32613091
http://dx.doi.org/10.1016/j.ctro.2020.06.007
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