Cargando…

miR-223-3p Inhibits Antigen Endocytosis and Presentation and Promotes the Tolerogenic Potential of Dendritic Cells through Targeting Mannose Receptor Signaling and Rhob

BACKGROUND: The role of miR-223-3p in dendritic cells (DCs) is unknown. This study is aimed at investigating the effect of miR-223-3p on the antigen uptake and presentation capacities of DCs and the underlying molecular mechanism. METHODS: FITC-OVA antigen uptake and cell surface markers in bone mar...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, Hao-Cheng, Lai, Yin-Yan, Zheng, Jing, Jiang, Hong-Yan, Xu, Geng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320286/
https://www.ncbi.nlm.nih.gov/pubmed/32656268
http://dx.doi.org/10.1155/2020/1379458