Presence of bla(PER-1) and bla(VEB-1) beta-lactamase genes among isolates of Pseudomonas aeruginosa from South West of Iran

Pseudomonas aeruginosa isolates have acquired resistance to antibiotics such as novel beta-lactams. The aim of this study was to investigate the bla(PER-1), bla(VEB-1), and bla(PSE-1) genes among isolates of P. aeruginosa among intensive care unit (ICU) patients. Sixty-five isolates were collected....

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Detalles Bibliográficos
Autores principales: Davodian, Elham, Sadeghifard, Nourkhoda, Ghasemian, Abdolmajid, Noorbakhsh, Samileh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Atlantis Press 2016
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320475/
https://www.ncbi.nlm.nih.gov/pubmed/26944896
http://dx.doi.org/10.1016/j.jegh.2016.02.002
Descripción
Sumario:Pseudomonas aeruginosa isolates have acquired resistance to antibiotics such as novel beta-lactams. The aim of this study was to investigate the bla(PER-1), bla(VEB-1), and bla(PSE-1) genes among isolates of P. aeruginosa among intensive care unit (ICU) patients. Sixty-five isolates were collected. The antibiotic susceptibility testing and combined disk tests were performed to detect the isolates producing extended spectrum beta-lactamases (ESBLs) among ceftazidime-resistant isolates. Polymerase chain reaction (PCR) amplification of bla(PER-1), bla(VEB-1), and bla(PSE-1) genes was conducted. Ten (15.3%) isolates were ESBL-positive, of which 40% (n = 4) belonged to males and 60% (n = 6) were collected from females. Moreover, two and one isolates harbored bla(PER-1) and bla(VEB-1) genes, respectively.

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