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Presence of bla(PER-1) and bla(VEB-1) beta-lactamase genes among isolates of Pseudomonas aeruginosa from South West of Iran
Pseudomonas aeruginosa isolates have acquired resistance to antibiotics such as novel beta-lactams. The aim of this study was to investigate the bla(PER-1), bla(VEB-1), and bla(PSE-1) genes among isolates of P. aeruginosa among intensive care unit (ICU) patients. Sixty-five isolates were collected....
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Atlantis Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320475/ https://www.ncbi.nlm.nih.gov/pubmed/26944896 http://dx.doi.org/10.1016/j.jegh.2016.02.002 |
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author | Davodian, Elham Sadeghifard, Nourkhoda Ghasemian, Abdolmajid Noorbakhsh, Samileh |
author_facet | Davodian, Elham Sadeghifard, Nourkhoda Ghasemian, Abdolmajid Noorbakhsh, Samileh |
author_sort | Davodian, Elham |
collection | PubMed |
description | Pseudomonas aeruginosa isolates have acquired resistance to antibiotics such as novel beta-lactams. The aim of this study was to investigate the bla(PER-1), bla(VEB-1), and bla(PSE-1) genes among isolates of P. aeruginosa among intensive care unit (ICU) patients. Sixty-five isolates were collected. The antibiotic susceptibility testing and combined disk tests were performed to detect the isolates producing extended spectrum beta-lactamases (ESBLs) among ceftazidime-resistant isolates. Polymerase chain reaction (PCR) amplification of bla(PER-1), bla(VEB-1), and bla(PSE-1) genes was conducted. Ten (15.3%) isolates were ESBL-positive, of which 40% (n = 4) belonged to males and 60% (n = 6) were collected from females. Moreover, two and one isolates harbored bla(PER-1) and bla(VEB-1) genes, respectively. |
format | Online Article Text |
id | pubmed-7320475 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Atlantis Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-73204752020-07-28 Presence of bla(PER-1) and bla(VEB-1) beta-lactamase genes among isolates of Pseudomonas aeruginosa from South West of Iran Davodian, Elham Sadeghifard, Nourkhoda Ghasemian, Abdolmajid Noorbakhsh, Samileh J Epidemiol Glob Health Short Communication Pseudomonas aeruginosa isolates have acquired resistance to antibiotics such as novel beta-lactams. The aim of this study was to investigate the bla(PER-1), bla(VEB-1), and bla(PSE-1) genes among isolates of P. aeruginosa among intensive care unit (ICU) patients. Sixty-five isolates were collected. The antibiotic susceptibility testing and combined disk tests were performed to detect the isolates producing extended spectrum beta-lactamases (ESBLs) among ceftazidime-resistant isolates. Polymerase chain reaction (PCR) amplification of bla(PER-1), bla(VEB-1), and bla(PSE-1) genes was conducted. Ten (15.3%) isolates were ESBL-positive, of which 40% (n = 4) belonged to males and 60% (n = 6) were collected from females. Moreover, two and one isolates harbored bla(PER-1) and bla(VEB-1) genes, respectively. Atlantis Press 2016 2016-03-02 /pmc/articles/PMC7320475/ /pubmed/26944896 http://dx.doi.org/10.1016/j.jegh.2016.02.002 Text en © 2016 Published by Elsevier Ltd. on behalf of Ministry of Health, Saudi Arabia. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/) |
spellingShingle | Short Communication Davodian, Elham Sadeghifard, Nourkhoda Ghasemian, Abdolmajid Noorbakhsh, Samileh Presence of bla(PER-1) and bla(VEB-1) beta-lactamase genes among isolates of Pseudomonas aeruginosa from South West of Iran |
title | Presence of bla(PER-1) and bla(VEB-1) beta-lactamase genes among isolates of Pseudomonas aeruginosa from South West of Iran |
title_full | Presence of bla(PER-1) and bla(VEB-1) beta-lactamase genes among isolates of Pseudomonas aeruginosa from South West of Iran |
title_fullStr | Presence of bla(PER-1) and bla(VEB-1) beta-lactamase genes among isolates of Pseudomonas aeruginosa from South West of Iran |
title_full_unstemmed | Presence of bla(PER-1) and bla(VEB-1) beta-lactamase genes among isolates of Pseudomonas aeruginosa from South West of Iran |
title_short | Presence of bla(PER-1) and bla(VEB-1) beta-lactamase genes among isolates of Pseudomonas aeruginosa from South West of Iran |
title_sort | presence of bla(per-1) and bla(veb-1) beta-lactamase genes among isolates of pseudomonas aeruginosa from south west of iran |
topic | Short Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320475/ https://www.ncbi.nlm.nih.gov/pubmed/26944896 http://dx.doi.org/10.1016/j.jegh.2016.02.002 |
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