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Resolving single-cell heterogeneity from hundreds of thousands of cells through sequential hybrid clustering and NMF
MOTIVATION: The rapid proliferation of single-cell RNA-sequencing (scRNA-Seq) technologies has spurred the development of diverse computational approaches to detect transcriptionally coherent populations. While the complexity of the algorithms for detecting heterogeneity has increased, most require...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320606/ https://www.ncbi.nlm.nih.gov/pubmed/32207533 http://dx.doi.org/10.1093/bioinformatics/btaa201 |