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Serpentine: a flexible 2D binning method for differential Hi-C analysis
MOTIVATION: Hi-C contact maps reflect the relative contact frequencies between pairs of genomic loci, quantified through deep sequencing. Differential analyses of these maps enable downstream biological interpretations. However, the multi-fractal nature of the chromatin polymer inside the cellular e...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320618/ https://www.ncbi.nlm.nih.gov/pubmed/32311033 http://dx.doi.org/10.1093/bioinformatics/btaa249 |