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Serpentine: a flexible 2D binning method for differential Hi-C analysis

MOTIVATION: Hi-C contact maps reflect the relative contact frequencies between pairs of genomic loci, quantified through deep sequencing. Differential analyses of these maps enable downstream biological interpretations. However, the multi-fractal nature of the chromatin polymer inside the cellular e...

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Detalles Bibliográficos
Autores principales: Baudry, Lyam, Millot, Gaël A, Thierry, Agnes, Koszul, Romain, Scolari, Vittore F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320618/
https://www.ncbi.nlm.nih.gov/pubmed/32311033
http://dx.doi.org/10.1093/bioinformatics/btaa249