SSPH I, a Novel Anti-Cancer Saponin, Inhibits Autophagy and Induces Apoptosis via ROS Accumulation and ERK1/2 Signaling Pathway in Hepatocellular Carcinoma Cells

INTRODUCTION: Saponin of Schizocapsa plantaginea Hance I (SSPH I), a novel bioactive phytochemical isolated from the rhizomes of Schizocapsa plantaginea, has been demonstrated to exhibit anti-cancer activity against various tumors in preclinical studies. However, the molecular mechanisms involved in...

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Detalles Bibliográficos
Autores principales: Zhou, Jin-ling, Huang, Xiu-ying, Qiu, Han-chen, Gan, Ri-zhi, Zhou, Huan, Zhu, Hong-qing, Zhang, Xuan-xuan, Lu, Guo-dong, Liang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320904/
https://www.ncbi.nlm.nih.gov/pubmed/32606806
http://dx.doi.org/10.2147/OTT.S253234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320904/
https://www.ncbi.nlm.nih.gov/pubmed/32606806
http://dx.doi.org/10.2147/OTT.S253234

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