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A Universal Design of Betacoronavirus Vaccines against COVID-19, MERS, and SARS

Vaccines are urgently needed to control the ongoing pandemic COVID-19 and previously emerging MERS/SARS caused by coronavirus (CoV) infections. The CoV spike receptor-binding domain (RBD) is an attractive vaccine target but is undermined by limited immunogenicity. We describe a dimeric form of MERS-...

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Detalles Bibliográficos
Autores principales: Dai, Lianpan, Zheng, Tianyi, Xu, Kun, Han, Yuxuan, Xu, Lili, Huang, Enqi, An, Yaling, Cheng, Yingjie, Li, Shihua, Liu, Mei, Yang, Mi, Li, Yan, Cheng, Huijun, Yuan, Yuan, Zhang, Wei, Ke, Changwen, Wong, Gary, Qi, Jianxun, Qin, Chuan, Yan, Jinghua, Gao, George F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321023/
https://www.ncbi.nlm.nih.gov/pubmed/32645327
http://dx.doi.org/10.1016/j.cell.2020.06.035