Rapid Mass Spectrometric Study of a Supercritical CO(2)-extract from Woody Liana Schisandra chinensis by HPLC-SPD-ESI-MS/MS

Woody liana Schisandra chinensis contains valuable lignans, which are phenylpropanoids with valuable biological activity. Among green and selective extraction methods, supercritical carbon dioxide (SC-CO(2)) was shown to be the method of choice for the recovery of these naturally occurring compounds...

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Autores principales: Razgonova, Mayya, Zakharenko, Alexander, Pikula, Konstantin, Kim, Ekaterina, Chernyshev, Valery, Ercisli, Sezai, Cravotto, Giancarlo, Golokhvast, Kirill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321071/
https://www.ncbi.nlm.nih.gov/pubmed/32531905
http://dx.doi.org/10.3390/molecules25112689
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author Razgonova, Mayya
Zakharenko, Alexander
Pikula, Konstantin
Kim, Ekaterina
Chernyshev, Valery
Ercisli, Sezai
Cravotto, Giancarlo
Golokhvast, Kirill
author_facet Razgonova, Mayya
Zakharenko, Alexander
Pikula, Konstantin
Kim, Ekaterina
Chernyshev, Valery
Ercisli, Sezai
Cravotto, Giancarlo
Golokhvast, Kirill
author_sort Razgonova, Mayya
collection PubMed
description Woody liana Schisandra chinensis contains valuable lignans, which are phenylpropanoids with valuable biological activity. Among green and selective extraction methods, supercritical carbon dioxide (SC-CO(2)) was shown to be the method of choice for the recovery of these naturally occurring compounds. Carbon dioxide (CO(2)) was the solvent with the flow rate (10−25 g/min) with 2% ethanol as co-solvent. In this piece of work operative parameters and working conditions were optimized by experimenting with different pressures (200–400 bars) and temperatures (40–60 °C). The extraction time varied from 60 to 120 min. HPLC-SPD-ESI -MS/MS techniques were applied to detect target analytes. Twenty-six different lignans were identified in the S. chinensis SC-CO(2) extracts.
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spelling pubmed-73210712020-07-06 Rapid Mass Spectrometric Study of a Supercritical CO(2)-extract from Woody Liana Schisandra chinensis by HPLC-SPD-ESI-MS/MS Razgonova, Mayya Zakharenko, Alexander Pikula, Konstantin Kim, Ekaterina Chernyshev, Valery Ercisli, Sezai Cravotto, Giancarlo Golokhvast, Kirill Molecules Article Woody liana Schisandra chinensis contains valuable lignans, which are phenylpropanoids with valuable biological activity. Among green and selective extraction methods, supercritical carbon dioxide (SC-CO(2)) was shown to be the method of choice for the recovery of these naturally occurring compounds. Carbon dioxide (CO(2)) was the solvent with the flow rate (10−25 g/min) with 2% ethanol as co-solvent. In this piece of work operative parameters and working conditions were optimized by experimenting with different pressures (200–400 bars) and temperatures (40–60 °C). The extraction time varied from 60 to 120 min. HPLC-SPD-ESI -MS/MS techniques were applied to detect target analytes. Twenty-six different lignans were identified in the S. chinensis SC-CO(2) extracts. MDPI 2020-06-10 /pmc/articles/PMC7321071/ /pubmed/32531905 http://dx.doi.org/10.3390/molecules25112689 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Razgonova, Mayya
Zakharenko, Alexander
Pikula, Konstantin
Kim, Ekaterina
Chernyshev, Valery
Ercisli, Sezai
Cravotto, Giancarlo
Golokhvast, Kirill
Rapid Mass Spectrometric Study of a Supercritical CO(2)-extract from Woody Liana Schisandra chinensis by HPLC-SPD-ESI-MS/MS
title Rapid Mass Spectrometric Study of a Supercritical CO(2)-extract from Woody Liana Schisandra chinensis by HPLC-SPD-ESI-MS/MS
title_full Rapid Mass Spectrometric Study of a Supercritical CO(2)-extract from Woody Liana Schisandra chinensis by HPLC-SPD-ESI-MS/MS
title_fullStr Rapid Mass Spectrometric Study of a Supercritical CO(2)-extract from Woody Liana Schisandra chinensis by HPLC-SPD-ESI-MS/MS
title_full_unstemmed Rapid Mass Spectrometric Study of a Supercritical CO(2)-extract from Woody Liana Schisandra chinensis by HPLC-SPD-ESI-MS/MS
title_short Rapid Mass Spectrometric Study of a Supercritical CO(2)-extract from Woody Liana Schisandra chinensis by HPLC-SPD-ESI-MS/MS
title_sort rapid mass spectrometric study of a supercritical co(2)-extract from woody liana schisandra chinensis by hplc-spd-esi-ms/ms
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321071/
https://www.ncbi.nlm.nih.gov/pubmed/32531905
http://dx.doi.org/10.3390/molecules25112689
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