N-Alkylaminoferrocene-Based Prodrugs Targeting Mitochondria of Cancer Cells

Intracellular concentration of reactive oxygen species (e.g., H(2)O(2)) in cancer cells is elevated over 10-fold as compared to normal cells. This feature has been used by us and several other research groups to design cancer specific prodrugs, for example, N-alkylaminoferrocene (NAAF)-based prodrug...

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Detalles Bibliográficos
Autores principales: Reshetnikov, Viktor, Özkan, Hülya Gizem, Daum, Steffen, Janko, Christina, Alexiou, Christoph, Sauer, Caroline, Heinrich, Markus R., Mokhir, Andriy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321169/
https://www.ncbi.nlm.nih.gov/pubmed/32486084
http://dx.doi.org/10.3390/molecules25112545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321169/
https://www.ncbi.nlm.nih.gov/pubmed/32486084
http://dx.doi.org/10.3390/molecules25112545

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