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N-Alkylaminoferrocene-Based Prodrugs Targeting Mitochondria of Cancer Cells
Intracellular concentration of reactive oxygen species (e.g., H(2)O(2)) in cancer cells is elevated over 10-fold as compared to normal cells. This feature has been used by us and several other research groups to design cancer specific prodrugs, for example, N-alkylaminoferrocene (NAAF)-based prodrug...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321169/ https://www.ncbi.nlm.nih.gov/pubmed/32486084 http://dx.doi.org/10.3390/molecules25112545 |