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Upscale Design, Process Development, and Economic Analysis of Industrial Plants for Nanomagnetic Particle Production for Environmental and Biomedical Use

Very few economical and process engineering studies have been made concerning the scale-up and implementation of nanomagnetic particle manufacturing into a full-scale plant, and determination of its viability. In this work we describe such a study for two types of industrial plants, one for manufact...

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Autores principales: Augusto, Paulo A., Castelo-Grande, Teresa, Vargas, Diana, Pascual, Alvaro, Hernández, Lorenzo, Estevez, Angel M., Barbosa, Domingos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321212/
https://www.ncbi.nlm.nih.gov/pubmed/32485890
http://dx.doi.org/10.3390/ma13112477
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author Augusto, Paulo A.
Castelo-Grande, Teresa
Vargas, Diana
Pascual, Alvaro
Hernández, Lorenzo
Estevez, Angel M.
Barbosa, Domingos
author_facet Augusto, Paulo A.
Castelo-Grande, Teresa
Vargas, Diana
Pascual, Alvaro
Hernández, Lorenzo
Estevez, Angel M.
Barbosa, Domingos
author_sort Augusto, Paulo A.
collection PubMed
description Very few economical and process engineering studies have been made concerning the scale-up and implementation of nanomagnetic particle manufacturing into a full-scale plant, and determination of its viability. In this work we describe such a study for two types of industrial plants, one for manufacturing magnetic particles for applications in the environmental area, and the other for manufacturing nanomagnetic particles for applications in the biotechnology area; the two different applications are compared. The following methodology was followed: establish the manufacturing process for each application; determine the market demand of the product (magnetic nanoparticles) for both applications; determine the production capacity of each plant; engineer all the manufacturing process, determining all the process units and performing all the mass and energy balances for both plants; scale-up the main equipment; and determine the global economic impact and profitability. At the end both plants are found to be technologically and economically viable, the characteristics of the final products being, however, quite different, as well as the process engineering, economic analysis, and scale-up.
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spelling pubmed-73212122020-07-06 Upscale Design, Process Development, and Economic Analysis of Industrial Plants for Nanomagnetic Particle Production for Environmental and Biomedical Use Augusto, Paulo A. Castelo-Grande, Teresa Vargas, Diana Pascual, Alvaro Hernández, Lorenzo Estevez, Angel M. Barbosa, Domingos Materials (Basel) Article Very few economical and process engineering studies have been made concerning the scale-up and implementation of nanomagnetic particle manufacturing into a full-scale plant, and determination of its viability. In this work we describe such a study for two types of industrial plants, one for manufacturing magnetic particles for applications in the environmental area, and the other for manufacturing nanomagnetic particles for applications in the biotechnology area; the two different applications are compared. The following methodology was followed: establish the manufacturing process for each application; determine the market demand of the product (magnetic nanoparticles) for both applications; determine the production capacity of each plant; engineer all the manufacturing process, determining all the process units and performing all the mass and energy balances for both plants; scale-up the main equipment; and determine the global economic impact and profitability. At the end both plants are found to be technologically and economically viable, the characteristics of the final products being, however, quite different, as well as the process engineering, economic analysis, and scale-up. MDPI 2020-05-29 /pmc/articles/PMC7321212/ /pubmed/32485890 http://dx.doi.org/10.3390/ma13112477 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Augusto, Paulo A.
Castelo-Grande, Teresa
Vargas, Diana
Pascual, Alvaro
Hernández, Lorenzo
Estevez, Angel M.
Barbosa, Domingos
Upscale Design, Process Development, and Economic Analysis of Industrial Plants for Nanomagnetic Particle Production for Environmental and Biomedical Use
title Upscale Design, Process Development, and Economic Analysis of Industrial Plants for Nanomagnetic Particle Production for Environmental and Biomedical Use
title_full Upscale Design, Process Development, and Economic Analysis of Industrial Plants for Nanomagnetic Particle Production for Environmental and Biomedical Use
title_fullStr Upscale Design, Process Development, and Economic Analysis of Industrial Plants for Nanomagnetic Particle Production for Environmental and Biomedical Use
title_full_unstemmed Upscale Design, Process Development, and Economic Analysis of Industrial Plants for Nanomagnetic Particle Production for Environmental and Biomedical Use
title_short Upscale Design, Process Development, and Economic Analysis of Industrial Plants for Nanomagnetic Particle Production for Environmental and Biomedical Use
title_sort upscale design, process development, and economic analysis of industrial plants for nanomagnetic particle production for environmental and biomedical use
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321212/
https://www.ncbi.nlm.nih.gov/pubmed/32485890
http://dx.doi.org/10.3390/ma13112477
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