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Upscale Design, Process Development, and Economic Analysis of Industrial Plants for Nanomagnetic Particle Production for Environmental and Biomedical Use
Very few economical and process engineering studies have been made concerning the scale-up and implementation of nanomagnetic particle manufacturing into a full-scale plant, and determination of its viability. In this work we describe such a study for two types of industrial plants, one for manufact...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321212/ https://www.ncbi.nlm.nih.gov/pubmed/32485890 http://dx.doi.org/10.3390/ma13112477 |
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author | Augusto, Paulo A. Castelo-Grande, Teresa Vargas, Diana Pascual, Alvaro Hernández, Lorenzo Estevez, Angel M. Barbosa, Domingos |
author_facet | Augusto, Paulo A. Castelo-Grande, Teresa Vargas, Diana Pascual, Alvaro Hernández, Lorenzo Estevez, Angel M. Barbosa, Domingos |
author_sort | Augusto, Paulo A. |
collection | PubMed |
description | Very few economical and process engineering studies have been made concerning the scale-up and implementation of nanomagnetic particle manufacturing into a full-scale plant, and determination of its viability. In this work we describe such a study for two types of industrial plants, one for manufacturing magnetic particles for applications in the environmental area, and the other for manufacturing nanomagnetic particles for applications in the biotechnology area; the two different applications are compared. The following methodology was followed: establish the manufacturing process for each application; determine the market demand of the product (magnetic nanoparticles) for both applications; determine the production capacity of each plant; engineer all the manufacturing process, determining all the process units and performing all the mass and energy balances for both plants; scale-up the main equipment; and determine the global economic impact and profitability. At the end both plants are found to be technologically and economically viable, the characteristics of the final products being, however, quite different, as well as the process engineering, economic analysis, and scale-up. |
format | Online Article Text |
id | pubmed-7321212 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-73212122020-07-06 Upscale Design, Process Development, and Economic Analysis of Industrial Plants for Nanomagnetic Particle Production for Environmental and Biomedical Use Augusto, Paulo A. Castelo-Grande, Teresa Vargas, Diana Pascual, Alvaro Hernández, Lorenzo Estevez, Angel M. Barbosa, Domingos Materials (Basel) Article Very few economical and process engineering studies have been made concerning the scale-up and implementation of nanomagnetic particle manufacturing into a full-scale plant, and determination of its viability. In this work we describe such a study for two types of industrial plants, one for manufacturing magnetic particles for applications in the environmental area, and the other for manufacturing nanomagnetic particles for applications in the biotechnology area; the two different applications are compared. The following methodology was followed: establish the manufacturing process for each application; determine the market demand of the product (magnetic nanoparticles) for both applications; determine the production capacity of each plant; engineer all the manufacturing process, determining all the process units and performing all the mass and energy balances for both plants; scale-up the main equipment; and determine the global economic impact and profitability. At the end both plants are found to be technologically and economically viable, the characteristics of the final products being, however, quite different, as well as the process engineering, economic analysis, and scale-up. MDPI 2020-05-29 /pmc/articles/PMC7321212/ /pubmed/32485890 http://dx.doi.org/10.3390/ma13112477 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Augusto, Paulo A. Castelo-Grande, Teresa Vargas, Diana Pascual, Alvaro Hernández, Lorenzo Estevez, Angel M. Barbosa, Domingos Upscale Design, Process Development, and Economic Analysis of Industrial Plants for Nanomagnetic Particle Production for Environmental and Biomedical Use |
title | Upscale Design, Process Development, and Economic Analysis of Industrial Plants for Nanomagnetic Particle Production for Environmental and Biomedical Use |
title_full | Upscale Design, Process Development, and Economic Analysis of Industrial Plants for Nanomagnetic Particle Production for Environmental and Biomedical Use |
title_fullStr | Upscale Design, Process Development, and Economic Analysis of Industrial Plants for Nanomagnetic Particle Production for Environmental and Biomedical Use |
title_full_unstemmed | Upscale Design, Process Development, and Economic Analysis of Industrial Plants for Nanomagnetic Particle Production for Environmental and Biomedical Use |
title_short | Upscale Design, Process Development, and Economic Analysis of Industrial Plants for Nanomagnetic Particle Production for Environmental and Biomedical Use |
title_sort | upscale design, process development, and economic analysis of industrial plants for nanomagnetic particle production for environmental and biomedical use |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321212/ https://www.ncbi.nlm.nih.gov/pubmed/32485890 http://dx.doi.org/10.3390/ma13112477 |
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