Acetamidine-Based iNOS Inhibitors as Molecular Tools to Counteract Inflammation in BV2 Microglial Cells

Neurodegenerative diseases are associated with increased levels of nitric oxide (NO) mainly produced by microglial cells through inducible nitric oxide synthase (iNOS) whose expression is induced by inflammatory stimuli. NO can both exert cytotoxic functions and induce a metabolic switch by inhibiti...

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Detalles Bibliográficos
Autores principales: Grottelli, Silvia, Amoroso, Rosa, Macchioni, Lara, D’Onofrio, Fiorella, Fettucciari, Katia, Bellezza, Ilaria, Maccallini, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321217/
https://www.ncbi.nlm.nih.gov/pubmed/32517272
http://dx.doi.org/10.3390/molecules25112646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321217/
https://www.ncbi.nlm.nih.gov/pubmed/32517272
http://dx.doi.org/10.3390/molecules25112646

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