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Unsaturated Fatty Acid-Induced Conformational Transitions and Aggregation of the Repeat Domain of Tau
Background: The intrinsically disordered, amyloidogenic protein Tau associates with diverse classes of molecules, including proteins, nucleic acids, and lipids. Mounting evidence suggests that fatty acid molecules could play a role in the dysfunction of this protein, however, their interaction with...
Autores principales: | Barracchia, Carlo Giorgio, Tira, Roberto, Parolini, Francesca, Munari, Francesca, Bubacco, Luigi, Spyroulias, Georgios A., D’Onofrio, Mariapina, Assfalg, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321374/ https://www.ncbi.nlm.nih.gov/pubmed/32545360 http://dx.doi.org/10.3390/molecules25112716 |
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