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Prevalence of onchocerciasis, attitudes and practices and the treatment coverage after 15 years of mass drug administration with ivermectin in the Tombel Health District, Cameroon

INTRODUCTION: Onchocerciasis is an infection caused by Onchocerca volvulus. It affects 37 million people of which 99% are in Africa. This study assessed the prevalence of onchocerciasis after 15 years of mass drug administration with ivermectin. METHODS: This was a population based cross sectional s...

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Autores principales: Nyagang, Sharon Mumah, Cumber, Samuel Nambile, Cho, Jerome Fru, Keka, Elsie Indah, Nkfusai, Claude Ngwayu, Wepngong, Emerson, Tsoka-Gwegweni, Joyce Mahlako, Fokam, Eric Bertrand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321683/
https://www.ncbi.nlm.nih.gov/pubmed/32637005
http://dx.doi.org/10.11604/pamj.2020.35.107.16036
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author Nyagang, Sharon Mumah
Cumber, Samuel Nambile
Cho, Jerome Fru
Keka, Elsie Indah
Nkfusai, Claude Ngwayu
Wepngong, Emerson
Tsoka-Gwegweni, Joyce Mahlako
Fokam, Eric Bertrand
author_facet Nyagang, Sharon Mumah
Cumber, Samuel Nambile
Cho, Jerome Fru
Keka, Elsie Indah
Nkfusai, Claude Ngwayu
Wepngong, Emerson
Tsoka-Gwegweni, Joyce Mahlako
Fokam, Eric Bertrand
author_sort Nyagang, Sharon Mumah
collection PubMed
description INTRODUCTION: Onchocerciasis is an infection caused by Onchocerca volvulus. It affects 37 million people of which 99% are in Africa. This study assessed the prevalence of onchocerciasis after 15 years of mass drug administration with ivermectin. METHODS: This was a population based cross sectional study. Questionnaires covering participants' identity and attitudes and practices of community respondents towards ivermectin were administered. The treatment coverage was obtained by review of records of mass drug administration from 1999 to 2015. The epidemiological evaluation of infection status was done by parasitological examination of skin snips and nodule palpation in individuals in five health areas of the district. RESULTS: A total of 400 participants were randomly selected. Of these, 56.0% were males, 62.0% single, 59.5% farmers and 98.0% Christians. Participants with good attitudes towards community directed treatment with ivermectin made up 80.5% while 47.8% of the participants had good practice. The highest treatment coverage achieved was 88.0% in 2010 while lowest was 57.0% in 2002. Less than 2% had microfilaria and 6.0% had nodules. There was no statistically significant difference in the prevalence of microfilaria with respect to age. There was a statistically significant difference in the distribution of nodules (χ(2)=73.6, p=0.001) among the different age groups. The greatest rate of infection (2.1%) was among farmers. CONCLUSION: This study showed that the prevalence reduced compared to other prevalence studies in Cameroon. The study area was hypo-endemic for onchocerciasis.
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spelling pubmed-73216832020-07-06 Prevalence of onchocerciasis, attitudes and practices and the treatment coverage after 15 years of mass drug administration with ivermectin in the Tombel Health District, Cameroon Nyagang, Sharon Mumah Cumber, Samuel Nambile Cho, Jerome Fru Keka, Elsie Indah Nkfusai, Claude Ngwayu Wepngong, Emerson Tsoka-Gwegweni, Joyce Mahlako Fokam, Eric Bertrand Pan Afr Med J Research INTRODUCTION: Onchocerciasis is an infection caused by Onchocerca volvulus. It affects 37 million people of which 99% are in Africa. This study assessed the prevalence of onchocerciasis after 15 years of mass drug administration with ivermectin. METHODS: This was a population based cross sectional study. Questionnaires covering participants' identity and attitudes and practices of community respondents towards ivermectin were administered. The treatment coverage was obtained by review of records of mass drug administration from 1999 to 2015. The epidemiological evaluation of infection status was done by parasitological examination of skin snips and nodule palpation in individuals in five health areas of the district. RESULTS: A total of 400 participants were randomly selected. Of these, 56.0% were males, 62.0% single, 59.5% farmers and 98.0% Christians. Participants with good attitudes towards community directed treatment with ivermectin made up 80.5% while 47.8% of the participants had good practice. The highest treatment coverage achieved was 88.0% in 2010 while lowest was 57.0% in 2002. Less than 2% had microfilaria and 6.0% had nodules. There was no statistically significant difference in the prevalence of microfilaria with respect to age. There was a statistically significant difference in the distribution of nodules (χ(2)=73.6, p=0.001) among the different age groups. The greatest rate of infection (2.1%) was among farmers. CONCLUSION: This study showed that the prevalence reduced compared to other prevalence studies in Cameroon. The study area was hypo-endemic for onchocerciasis. The African Field Epidemiology Network 2020-04-08 /pmc/articles/PMC7321683/ /pubmed/32637005 http://dx.doi.org/10.11604/pamj.2020.35.107.16036 Text en © Sharon Mumah Nyagang et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Nyagang, Sharon Mumah
Cumber, Samuel Nambile
Cho, Jerome Fru
Keka, Elsie Indah
Nkfusai, Claude Ngwayu
Wepngong, Emerson
Tsoka-Gwegweni, Joyce Mahlako
Fokam, Eric Bertrand
Prevalence of onchocerciasis, attitudes and practices and the treatment coverage after 15 years of mass drug administration with ivermectin in the Tombel Health District, Cameroon
title Prevalence of onchocerciasis, attitudes and practices and the treatment coverage after 15 years of mass drug administration with ivermectin in the Tombel Health District, Cameroon
title_full Prevalence of onchocerciasis, attitudes and practices and the treatment coverage after 15 years of mass drug administration with ivermectin in the Tombel Health District, Cameroon
title_fullStr Prevalence of onchocerciasis, attitudes and practices and the treatment coverage after 15 years of mass drug administration with ivermectin in the Tombel Health District, Cameroon
title_full_unstemmed Prevalence of onchocerciasis, attitudes and practices and the treatment coverage after 15 years of mass drug administration with ivermectin in the Tombel Health District, Cameroon
title_short Prevalence of onchocerciasis, attitudes and practices and the treatment coverage after 15 years of mass drug administration with ivermectin in the Tombel Health District, Cameroon
title_sort prevalence of onchocerciasis, attitudes and practices and the treatment coverage after 15 years of mass drug administration with ivermectin in the tombel health district, cameroon
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321683/
https://www.ncbi.nlm.nih.gov/pubmed/32637005
http://dx.doi.org/10.11604/pamj.2020.35.107.16036
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