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Tumor suppressor p53 regulates insulin receptor (INSR) gene expression via direct binding to the INSR promoter
A significant volume of clinical and epidemiological data provides support to the concept that insulin and the insulin receptor (INSR) have an important role in breast cancer. Tumor suppressor p53 is the most frequently mutated molecule in human cancer. The present study was aimed at evaluating the...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321701/ https://www.ncbi.nlm.nih.gov/pubmed/32637033 http://dx.doi.org/10.18632/oncotarget.27645 |