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Tumor suppressor p53 regulates insulin receptor (INSR) gene expression via direct binding to the INSR promoter

A significant volume of clinical and epidemiological data provides support to the concept that insulin and the insulin receptor (INSR) have an important role in breast cancer. Tumor suppressor p53 is the most frequently mutated molecule in human cancer. The present study was aimed at evaluating the...

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Detalles Bibliográficos
Autores principales: Sarfstein, Rive, Werner, Haim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321701/
https://www.ncbi.nlm.nih.gov/pubmed/32637033
http://dx.doi.org/10.18632/oncotarget.27645