Integra(Ⓡ) dermal regeneration template as the nidus of staphylococcal toxic shock syndrome: A case report

The literature describes numerous successful applications using dermal regeneration templates such as Integra(Ⓡ). Despite widespread use for burns, trauma, and chronic wounds among others, Integra has associated complications which need continued investigation. Large multi-center studies designed to investigate its safety have shown that infections are the most common complications. In this case report, we share our experience with a patient who developed toxic shock syndrome (TSS) following abdominal scar revision with Integra. The literature reviewed identified one report of TSS in association with Integra use, which was fatal. In our case, the patient recovered uneventfully as a result of early recognition, expedient debridement, and appropriate antibiotic administration. Acknowledging that TSS is a rare but potential complication associated with the use of Integra is crucial for early recognition which will improve patient outcomes and reduces mortality.