Elimination of MYCN-Amplified Neuroblastoma Cells by Telomerase-Targeted Oncolytic Virus via MYCN Suppression

Neuroblastoma (NB) is a primary malignant tumor of the peripheral sympathetic nervous system. High-risk NB is characterized by MYCN amplification and human telomerase reverse transcriptase (hTERT) rearrangement, contributing to hTERT activation and a poor outcome. For targeting hTERT-activated tumor...

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Detalles Bibliográficos
Autores principales: Tanimoto, Terutaka, Tazawa, Hiroshi, Ieda, Takeshi, Nouso, Hiroshi, Tani, Morimichi, Oyama, Takanori, Urata, Yasuo, Kagawa, Shunsuke, Noda, Takuo, Fujiwara, Toshiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321810/
https://www.ncbi.nlm.nih.gov/pubmed/32637577
http://dx.doi.org/10.1016/j.omto.2020.05.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321810/
https://www.ncbi.nlm.nih.gov/pubmed/32637577
http://dx.doi.org/10.1016/j.omto.2020.05.015

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