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Hypomethylation Causes MIR21 Overexpression in Tumors

miR-21 is an oncogenic microRNA (miRNA) that is upregulated in many solid tumors. However, the effect of MIR21 hypomethylation on miR-21 expression in tumors and the mechanism of miR-21 DNA demethylation remain unclear. In this study, we confirmed that the expression of miR-21 was significantly incr...

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Detalles Bibliográficos
Autores principales:	Lu, Jun, Tan, Ting, Zhu, Ling, Dong, Huiyue, Xian, Ronghua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321816/ https://www.ncbi.nlm.nih.gov/pubmed/32637580 http://dx.doi.org/10.1016/j.omto.2020.05.011

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