Cargando…

Epigenetic Protection of Vertebrate Lymphoid Progenitor Cells by Dnmt1

DNA methylation is a universal epigenetic mechanism involved in regulation of gene expression and genome stability. The DNA maintenance methylase DNMT1 ensures that DNA methylation patterns are faithfully transmitted to daughter cells during cell division. Because loss of DNMT1 is lethal, a pan-orga...

Descripción completa

Detalles Bibliográficos
Autores principales:	Iwanami, Norimasa, Takeshita, Kohei, Lawir, Divine-Fondzenyuy, Suetake, Isao, Tajima, Shoji, Sikora, Katarzyna, Trancoso, Inês, ÓMeara, Connor, Siamishi, Iliana, Takahama, Yousuke, Furutani-Seiki, Makoto, Kondoh, Hisato, Yonezawa, Yasushige, Schorpp, Michael, Boehm, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322073/ https://www.ncbi.nlm.nih.gov/pubmed/32585597 http://dx.doi.org/10.1016/j.isci.2020.101260

Ejemplares similares

Evolutionary transition from degenerate to nonredundant cytokine signaling networks supporting intrathymic T cell development
por: Lawir, Divine-Fondzenyuy, et al.
Publicado: (2019)

A missense mutation in zbtb17 blocks the earliest steps of T cell differentiation in zebrafish
por: Lawir, Divine-Fondzenyuy, et al.
Publicado: (2017)

Genetic landscape of T cells identifies synthetic lethality for T-ALL
por: O’Meara, Connor P., et al.
Publicado: (2021)

Transgenerational inheritance of impaired larval T cell development in zebrafish
por: Iwanami, Norimasa, et al.
Publicado: (2020)

Pervasive changes of mRNA splicing in upf1-deficient zebrafish identify rpl10a as a regulator of T cell development
por: Lawir, Divine-Fondzenyuy, et al.
Publicado: (2020)

Forward Genetic Screens in Zebrafish Identify Pre-mRNA-Processing Pathways Regulating Early T Cell Development
por: Iwanami, Norimasa, et al.
Publicado: (2016)

A novel method to analyze 5-hydroxymethylcytosine in CpG sequences using maintenance DNA methyltransferase, DNMT1
por: Takahashi, Saori, et al.
Publicado: (2015)

WDR55 Is a Nucleolar Modulator of Ribosomal RNA Synthesis, Cell Cycle Progression, and Teleost Organ Development
por: Iwanami, Norimasa, et al.
Publicado: (2008)

Correction: WDR55 Is a Nucleolar Modulator of Ribosomal RNA Synthesis, Cell Cycle Progression, and Teleost Organ Development
por: Iwanami, Norimasa, et al.
Publicado: (2008)

DNMT1 regulates the timing of DNA methylation by DNMT3 in an enzymatic activity-dependent manner in mouse embryonic stem cells
por: Ito, Takamasa, et al.
Publicado: (2022)

Mutation in cpsf6/CFIm68 (Cleavage and Polyadenylation Specificity Factor Subunit 6) causes short 3'UTRs and disturbs gene expression in developing embryos, as revealed by an analysis of primordial germ cell migration using the medaka mutant naruto
por: Sasado, Takao, et al.
Publicado: (2017)

Tnpo3 controls splicing of the pre-mRNA encoding the canonical TCR α chain of iNKT cells
por: Iwanami, Norimasa, et al.
Publicado: (2023)

Cbfβ2 controls differentiation of and confers homing capacity to prethymic progenitors
por: Tenno, Mari, et al.
Publicado: (2018)

Dual Functions of the RFTS Domain of Dnmt1 in Replication-Coupled DNA Methylation and in Protection of the Genome from Aberrant Methylation
por: Garvilles, Ronald Garingalao, et al.
Publicado: (2015)

Evolution of thymopoietic microenvironments
por: Morimoto, Ryo, et al.
Publicado: (2021)

Synaptic control of DNA methylation involves activity-dependent degradation of DNMT3A1 in the nucleus
por: Bayraktar, Gonca, et al.
Publicado: (2020)

Antigen receptor repertoires of one of the smallest known vertebrates
por: Giorgetti, Orlando B., et al.
Publicado: (2021)

Expansions, diversification, and interindividual copy number variations of AID/APOBEC family cytidine deaminase genes in lampreys
por: Holland, Stephen J., et al.
Publicado: (2018)

Origin and evolutionary malleability of T cell receptor α diversity
por: Giorgetti, Orlando B., et al.
Publicado: (2023)

Limits to in vivo fate changes of epithelia in thymus and parathyroid by ectopic expression of transcription factors Gcm2 and Foxn1
por: Nagakubo, Daisuke, et al.
Publicado: (2022)

Clonal dynamics underlying the skewed CD4/CD8 ratio of mouse thymocytes revealed by TCR-independent barcoding
por: Iwanami, Norimasa, et al.
Publicado: (2022)

The DNMT3A ADD domain is required for efficient de novo DNA methylation and maternal imprinting in mouse oocytes
por: Uehara, Ryuji, et al.
Publicado: (2023)

Mutational effects of Cys113 on structural dynamics of Pin1
por: Ikura, Teikichi, et al.
Publicado: (2019)

Autoencoder-based detection of the residues involved in G protein-coupled receptor signaling
por: Tsuchiya, Yuko, et al.
Publicado: (2021)

Co-evolution of mutagenic genome editors and vertebrate adaptive immunity
por: Trancoso, Inês, et al.
Publicado: (2020)

A Novel method for the simultaneous identification of methylcytosine and hydroxymethylcytosine at a single base resolution
por: Kawasaki, Yuki, et al.
Publicado: (2017)

Development of massive multilevel molecular dynamics simulation program, platypus (PLATform for dYnamic protein unified simulation), for the elucidation of protein functions
por: Takano, Yu, et al.
Publicado: (2016)

Loosening of Side-Chain Packing Associated with Perturbations in Peripheral Dynamics Induced by the D76N Mutation of β(2)-Microglobulin Revealed by Pressure-NMR and Molecular Dynamic Simulations
por: Sakurai, Kazumasa, et al.
Publicado: (2019)

Radiation Hybrid Maps of Medaka Chromosomes LG 12, 17, and 22
por: Su, Feng, et al.
Publicado: (2007)

Apoptosis-Related Gene Expression Profiles of Mouse ESCs and maGSCs: Role of Fgf4 and Mnda in Pluripotent Cell Responses to Genotoxicity
por: Khromov, Tatjana, et al.
Publicado: (2012)

mTEC damage risks immune recovery
por: Takahama, Yousuke
Publicado: (2021)

Modulation of Dnmt3b function in vitro by interactions with Dnmt3L, Dnmt3a and Dnmt3b splice variants
por: Van Emburgh, Beth O., et al.
Publicado: (2011)

Generation of medaka gene knockout models by target-selected mutagenesis
por: Taniguchi, Yoshihito, et al.
Publicado: (2006)

Tnpo3 enables EBF1 function in conditions of antagonistic Notch signaling
por: Bayer, Marc, et al.
Publicado: (2022)

Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells
por: Liao, Jing, et al.
Publicado: (2015)

Oncogenic Roles and Inhibitors of DNMT1, DNMT3A, and DNMT3B in Acute Myeloid Leukaemia
por: Wong, Kah Keng, et al.
Publicado: (2019)

Evidence for a Role of the Transcriptional Regulator Maid in Tumorigenesis and Aging
por: Fujisawa, Koichi, et al.
Publicado: (2015)

Correction: Evidence for a Role of the Transcriptional Regulator Maid in Tumorigenesis and Aging
por: Fujisawa, Koichi, et al.
Publicado: (2015)

Specific impact of β5t on proteasome subunit composition in cortical thymic epithelial cells
por: Ohigashi, Izumi, et al.
Publicado: (2021)

DNMT1, DNMT3A and DNMT3B gene variants in relation to ovarian cancer risk in the Polish population
por: Mostowska, Adrianna, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_lqkhdjqii9onmm1ao94vhtabjt