The Accumulation of Tau-Immunoreactive Hippocampal Granules and Corpora Amylacea Implicates Reactive Glia in Tau Pathogenesis during Aging

The microtubule-associated tau protein forms pathological inclusions that accumulate in an age-dependent manner in tauopathies including Alzheimer's disease (AD). Since age is the major risk factor for AD, we examined endogenous tau species that evolve during aging in physiological and diseased...

Descripción completa

Detalles Bibliográficos
Autores principales: Wander, Connor M., Tseng, Jui-Heng, Song, Sheng, Al Housseiny, Heba A., Tart, Dalton S., Ajit, Aditi, Ian Shih, Yen-Yu, Lobrovich, Rebecca, Song, Juan, Meeker, Rick B., Irwin, David J., Cohen, Todd J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322077/
https://www.ncbi.nlm.nih.gov/pubmed/32585593
http://dx.doi.org/10.1016/j.isci.2020.101255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322077/
https://www.ncbi.nlm.nih.gov/pubmed/32585593
http://dx.doi.org/10.1016/j.isci.2020.101255

Ejemplares similares