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The Accumulation of Tau-Immunoreactive Hippocampal Granules and Corpora Amylacea Implicates Reactive Glia in Tau Pathogenesis during Aging

The microtubule-associated tau protein forms pathological inclusions that accumulate in an age-dependent manner in tauopathies including Alzheimer's disease (AD). Since age is the major risk factor for AD, we examined endogenous tau species that evolve during aging in physiological and diseased...

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Detalles Bibliográficos
Autores principales:	Wander, Connor M., Tseng, Jui-Heng, Song, Sheng, Al Housseiny, Heba A., Tart, Dalton S., Ajit, Aditi, Ian Shih, Yen-Yu, Lobrovich, Rebecca, Song, Juan, Meeker, Rick B., Irwin, David J., Cohen, Todd J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322077/ https://www.ncbi.nlm.nih.gov/pubmed/32585593 http://dx.doi.org/10.1016/j.isci.2020.101255

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