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Nasal spindle cell sarcoma: A case report

BACKGROUND: Synovial sarcoma is a mesenchymal high grade tumor. It is found in soft tissue mostly lower extremities. It is rarely found in the head and neck area with paraspinal neck accounting for the most common location. In rare occasions, it can be found in nasal cavity. CASE PRESENTATION: A 46-...

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Autores principales: Almahdi, Mohammad, ALRashed ALHumaid, Salwa, Alsafi, Maryam, AlObaid, Fahad, Alsalim, Alaa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322102/
https://www.ncbi.nlm.nih.gov/pubmed/32698278
http://dx.doi.org/10.1016/j.ijscr.2020.05.092
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author Almahdi, Mohammad
ALRashed ALHumaid, Salwa
Alsafi, Maryam
AlObaid, Fahad
Alsalim, Alaa
author_facet Almahdi, Mohammad
ALRashed ALHumaid, Salwa
Alsafi, Maryam
AlObaid, Fahad
Alsalim, Alaa
author_sort Almahdi, Mohammad
collection PubMed
description BACKGROUND: Synovial sarcoma is a mesenchymal high grade tumor. It is found in soft tissue mostly lower extremities. It is rarely found in the head and neck area with paraspinal neck accounting for the most common location. In rare occasions, it can be found in nasal cavity. CASE PRESENTATION: A 46-year-old female patient presented with recurrent epistaxis for 7 months. A 0-degree rigid scope examination revealed a left nasal cavity mass. A non-contrasted CT scan of the paranasal sinus showed heterogeneous and hypodense lesion in the left nasal cavity. Functional endoscopic sinus surgery was performed and multiple nasal-mass biopsies were taken which showed high grade spindle cell sarcoma favoring synovial type. Further workup and management were done from MRI, cranial tumor resection with skull base reconstruction to adjuvant radiotherapy. Patient has regular follow up with involved specialties and thus far is doing well. CONCLUSION: Spindle cell synovial sarcoma is a rare lesion found in soft tissue. It is unusual to be found in nasal cavity. Thus crucial attention to the clinical, radiographical and histopathological manifestation should be taken for more accurate diagnosis and further appropriate management.
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spelling pubmed-73221022020-06-30 Nasal spindle cell sarcoma: A case report Almahdi, Mohammad ALRashed ALHumaid, Salwa Alsafi, Maryam AlObaid, Fahad Alsalim, Alaa Int J Surg Case Rep Article BACKGROUND: Synovial sarcoma is a mesenchymal high grade tumor. It is found in soft tissue mostly lower extremities. It is rarely found in the head and neck area with paraspinal neck accounting for the most common location. In rare occasions, it can be found in nasal cavity. CASE PRESENTATION: A 46-year-old female patient presented with recurrent epistaxis for 7 months. A 0-degree rigid scope examination revealed a left nasal cavity mass. A non-contrasted CT scan of the paranasal sinus showed heterogeneous and hypodense lesion in the left nasal cavity. Functional endoscopic sinus surgery was performed and multiple nasal-mass biopsies were taken which showed high grade spindle cell sarcoma favoring synovial type. Further workup and management were done from MRI, cranial tumor resection with skull base reconstruction to adjuvant radiotherapy. Patient has regular follow up with involved specialties and thus far is doing well. CONCLUSION: Spindle cell synovial sarcoma is a rare lesion found in soft tissue. It is unusual to be found in nasal cavity. Thus crucial attention to the clinical, radiographical and histopathological manifestation should be taken for more accurate diagnosis and further appropriate management. Elsevier 2020-06-11 /pmc/articles/PMC7322102/ /pubmed/32698278 http://dx.doi.org/10.1016/j.ijscr.2020.05.092 Text en © 2020 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Almahdi, Mohammad
ALRashed ALHumaid, Salwa
Alsafi, Maryam
AlObaid, Fahad
Alsalim, Alaa
Nasal spindle cell sarcoma: A case report
title Nasal spindle cell sarcoma: A case report
title_full Nasal spindle cell sarcoma: A case report
title_fullStr Nasal spindle cell sarcoma: A case report
title_full_unstemmed Nasal spindle cell sarcoma: A case report
title_short Nasal spindle cell sarcoma: A case report
title_sort nasal spindle cell sarcoma: a case report
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322102/
https://www.ncbi.nlm.nih.gov/pubmed/32698278
http://dx.doi.org/10.1016/j.ijscr.2020.05.092
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