Cargando…

Composite Outcomes of Mortality and Readmission in Patients with Heart Failure: Retrospective Review of Administrative Datasets

BACKGROUND: Controlling the quality of care through readmissions and mortality for patients with heart failure (HF) is a national priority for healthcare regulators in developed countries. In this longitudinal cohort study, using administrative data such as hospital discharge forms (HDFs), emergency...

Descripción completa

Detalles Bibliográficos
Autores principales: Roshanghalb, Afsaneh, Mazzali, Cristina, Lettieri, Emanuele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322138/
https://www.ncbi.nlm.nih.gov/pubmed/32612362
http://dx.doi.org/10.2147/JMDH.S255206
_version_ 1783551584929579008
author Roshanghalb, Afsaneh
Mazzali, Cristina
Lettieri, Emanuele
author_facet Roshanghalb, Afsaneh
Mazzali, Cristina
Lettieri, Emanuele
author_sort Roshanghalb, Afsaneh
collection PubMed
description BACKGROUND: Controlling the quality of care through readmissions and mortality for patients with heart failure (HF) is a national priority for healthcare regulators in developed countries. In this longitudinal cohort study, using administrative data such as hospital discharge forms (HDFs), emergency departments (EDs) accesses, and vital statistics, we test new covariates for predicting mortality and readmissions of patients hospitalized for HF and discuss the use of combined outcome as an alternative. METHODS: Logistic models, with a stepwise selection method, were estimated on 70% of the sample and validated on the remaining 30% to evaluate 30-day mortality, 30-day readmissions, and the combined outcome. We followed an extraction method for any-cause mortality and unplanned readmission within 30 days after incident HF hospitalization. Data on patient admission and previous history were extracted by HDFs and ED dataset. RESULTS: Our principal findings demonstrate that the model’s discriminant ability is consistent with literature both for mortality (AUC=0.738, CI (0.729–0.748)) and readmissions (AUC=0.578, CI (0.562–0.594)). Additionally, the discriminant ability of the composite outcome model is satisfactory (AUC=0.675, CI (0.666–0.684)). CONCLUSION: Hospitalization characteristics and patient history introduced in the logistic models do not improve their discriminant ability. The composite outcome prediction is led more by mortality than readmission, without improvements for the comprehension of the readmission phenomenon.
format Online
Article
Text
id pubmed-7322138
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Dove
record_format MEDLINE/PubMed
spelling pubmed-73221382020-06-30 Composite Outcomes of Mortality and Readmission in Patients with Heart Failure: Retrospective Review of Administrative Datasets Roshanghalb, Afsaneh Mazzali, Cristina Lettieri, Emanuele J Multidiscip Healthc Original Research BACKGROUND: Controlling the quality of care through readmissions and mortality for patients with heart failure (HF) is a national priority for healthcare regulators in developed countries. In this longitudinal cohort study, using administrative data such as hospital discharge forms (HDFs), emergency departments (EDs) accesses, and vital statistics, we test new covariates for predicting mortality and readmissions of patients hospitalized for HF and discuss the use of combined outcome as an alternative. METHODS: Logistic models, with a stepwise selection method, were estimated on 70% of the sample and validated on the remaining 30% to evaluate 30-day mortality, 30-day readmissions, and the combined outcome. We followed an extraction method for any-cause mortality and unplanned readmission within 30 days after incident HF hospitalization. Data on patient admission and previous history were extracted by HDFs and ED dataset. RESULTS: Our principal findings demonstrate that the model’s discriminant ability is consistent with literature both for mortality (AUC=0.738, CI (0.729–0.748)) and readmissions (AUC=0.578, CI (0.562–0.594)). Additionally, the discriminant ability of the composite outcome model is satisfactory (AUC=0.675, CI (0.666–0.684)). CONCLUSION: Hospitalization characteristics and patient history introduced in the logistic models do not improve their discriminant ability. The composite outcome prediction is led more by mortality than readmission, without improvements for the comprehension of the readmission phenomenon. Dove 2020-06-24 /pmc/articles/PMC7322138/ /pubmed/32612362 http://dx.doi.org/10.2147/JMDH.S255206 Text en © 2020 Roshanghalb et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Roshanghalb, Afsaneh
Mazzali, Cristina
Lettieri, Emanuele
Composite Outcomes of Mortality and Readmission in Patients with Heart Failure: Retrospective Review of Administrative Datasets
title Composite Outcomes of Mortality and Readmission in Patients with Heart Failure: Retrospective Review of Administrative Datasets
title_full Composite Outcomes of Mortality and Readmission in Patients with Heart Failure: Retrospective Review of Administrative Datasets
title_fullStr Composite Outcomes of Mortality and Readmission in Patients with Heart Failure: Retrospective Review of Administrative Datasets
title_full_unstemmed Composite Outcomes of Mortality and Readmission in Patients with Heart Failure: Retrospective Review of Administrative Datasets
title_short Composite Outcomes of Mortality and Readmission in Patients with Heart Failure: Retrospective Review of Administrative Datasets
title_sort composite outcomes of mortality and readmission in patients with heart failure: retrospective review of administrative datasets
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322138/
https://www.ncbi.nlm.nih.gov/pubmed/32612362
http://dx.doi.org/10.2147/JMDH.S255206
work_keys_str_mv AT roshanghalbafsaneh compositeoutcomesofmortalityandreadmissioninpatientswithheartfailureretrospectivereviewofadministrativedatasets
AT mazzalicristina compositeoutcomesofmortalityandreadmissioninpatientswithheartfailureretrospectivereviewofadministrativedatasets
AT lettieriemanuele compositeoutcomesofmortalityandreadmissioninpatientswithheartfailureretrospectivereviewofadministrativedatasets