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Itaconate prevents abdominal aortic aneurysm formation through inhibiting inflammation via activation of Nrf2
BACKGROUND: Identifying effective drugs to suppress vascular inflammation is a promising strategy to delay the progression of abdominal aortic aneurysm (AAA). Itaconate has a vital role in regulating inflammatory activation in various inflammatory diseases. However, the role of itaconate in the prog...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322255/ https://www.ncbi.nlm.nih.gov/pubmed/32574955 http://dx.doi.org/10.1016/j.ebiom.2020.102832 |