Incidental primary breast cancer detected on surveillance (68)Ga-DOTATATE PET/CT in a patient with metastatic neuroendocrine carcinoma

We present a case of a 53-year-old woman with metastatic neuroendocrine tumor, presumed primary in the small intestine with metastases to the liver and mesenteric lymph nodes. The patient was being treated with lanreotide and followed with somatostatin receptor (SSTR)-targeted 68Ga-labeled 1,4,7,10-...

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Detalles Bibliográficos
Autores principales: Ambinder, Emily B., Werner, Rudolf A., Rowe, Steven P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Breast Imaging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322489/
https://www.ncbi.nlm.nih.gov/pubmed/32617128
http://dx.doi.org/10.1016/j.radcr.2020.05.054
Descripción
Sumario:We present a case of a 53-year-old woman with metastatic neuroendocrine tumor, presumed primary in the small intestine with metastases to the liver and mesenteric lymph nodes. The patient was being treated with lanreotide and followed with somatostatin receptor (SSTR)-targeted 68Ga-labeled 1,4,7,10-tetraazacyclododecane-N,N', N'',N'''-tetraacetic acid-d-Phe(1)-Tyr(3)-octreotate ((68)Ga-DOTATATE) positron emission tomography – computed tomography (PET/CT). On a follow-up exam, the patient's primary and metastatic disease had improved but she had new (68)Ga-DOTATATE-avid lesions in the right breast and right axilla. Subsequent breast imaging workup and biopsy demonstrated a primary breast cancer and axillary lymph node metastasis.

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