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Twist1 induces chromosomal instability (CIN) in colorectal cancer cells

Twist1 is a basic helix-loop-helix transcription factor, essential during early development in mammals. While Twist1 induces epithelial-to-mesenchymal transition (EMT), here we show that Twist1 overexpression enhances nuclear and mitotic aberrations. This is accompanied by an increase in whole chrom...

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Detalles Bibliográficos
Autores principales:	Khot, Maithilee, Sreekumar, Dyuthi, Jahagirdar, Sanika, Kulkarni, Apoorva, Hari, Kishore, Faseela, Elangoli Ebrahimkutty, Sabarinathan, Radhakrishnan, Jolly, Mohit Kumar, Sengupta, Kundan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	General Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322571/ https://www.ncbi.nlm.nih.gov/pubmed/32337580 http://dx.doi.org/10.1093/hmg/ddaa076

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