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ALS-associated genes in SCA2 mouse spinal cord transcriptomes

The spinocerebellar ataxia type 2 (SCA2) gene ATXN2 has a prominent role in the pathogenesis and treatment of amyotrophic lateral sclerosis (ALS). In addition to cerebellar ataxia, motor neuron disease is often seen in SCA2, and ATXN2 CAG repeat expansions in the long normal range increase ALS risk....

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Detalles Bibliográficos
Autores principales:	Scoles, Daniel R, Dansithong, Warunee, Pflieger, Lance T, Paul, Sharan, Gandelman, Mandi, Figueroa, Karla P, Rigo, Frank, Bennett, C Frank, Pulst, Stefan M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	General Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322574/ https://www.ncbi.nlm.nih.gov/pubmed/32307524 http://dx.doi.org/10.1093/hmg/ddaa072

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