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Dexmedetomidine Attenuates Neurotoxicity in Developing Rats Induced by Sevoflurane through Upregulating BDNF-TrkB-CREB and Downregulating ProBDNF-P75NRT-RhoA Signaling Pathway
To investigate the mechanism dexmedetomidine in relieving the neurotoxicity of a developing brain induced by sevoflurane. Sprague-Dawley rats, 6 days old, were randomly divided into three groups. Rats in the control group were inhaled with air after injection of normal saline; rats in the sevofluran...
Autores principales: | Dong, Yunxia, Hong, Wei, Tang, Zhiyin, Gao, Yan, Wu, Xiuying, Liu, Hongtao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322616/ https://www.ncbi.nlm.nih.gov/pubmed/32655312 http://dx.doi.org/10.1155/2020/5458061 |
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