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Dexmedetomidine Attenuates Neurotoxicity in Developing Rats Induced by Sevoflurane through Upregulating BDNF-TrkB-CREB and Downregulating ProBDNF-P75NRT-RhoA Signaling Pathway

To investigate the mechanism dexmedetomidine in relieving the neurotoxicity of a developing brain induced by sevoflurane. Sprague-Dawley rats, 6 days old, were randomly divided into three groups. Rats in the control group were inhaled with air after injection of normal saline; rats in the sevofluran...

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Detalles Bibliográficos
Autores principales: Dong, Yunxia, Hong, Wei, Tang, Zhiyin, Gao, Yan, Wu, Xiuying, Liu, Hongtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322616/
https://www.ncbi.nlm.nih.gov/pubmed/32655312
http://dx.doi.org/10.1155/2020/5458061

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