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Increasing the power of randomized trials comparing different treatment durations

When the optimal treatment duration is uncertain, a randomized trial may allocate patients to receive active treatment for different durations. We use an example where patients receive treatment for 0, 24, or 52 weeks. In this trial, patients in the 24-weeks and 52-weeks arms receive the same treatm...

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Detalles Bibliográficos
Autores principales: Ouyang, Yongdong, Qian, Hong, Yatham, Lakshmi N., Wong, Hubert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322686/
https://www.ncbi.nlm.nih.gov/pubmed/32617431
http://dx.doi.org/10.1016/j.conctc.2020.100588