Cargando…

Impact of pantoprazole on absorption and disposition of hydroxychloroquine, a drug used in Corona Virus Disease-19 (Covid-19): A structured summary of a study protocol for a randomised controlled trial

OBJECTIVES: Primary objective: Evaluation of the effect of the proton pump inhibitor (PPI) pantoprazole on the absorption of hydroxychloroquine (HCQ). Secondary objectives: • Evaluation of the relationship between HCQ concentrations in whole blood, plasma and intracellular concentrations in target c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Stoll, Felicitas, Blank, Antje, Mikus, Gerd, Czock, David, Foerster, Kathrin I., Hermann, Simon, Häußler, Katja, Muhareb, Amin, Hummler, Simone, Weiss, Johanna, Burhenne, Jürgen, Haefeli, Walter E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Letter
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322698/ https://www.ncbi.nlm.nih.gov/pubmed/32600363 http://dx.doi.org/10.1186/s13063-020-04476-y

Ejemplares similares

CYP3A and CYP2C19 Activity Determined by Microdosed Probe Drugs Accurately Predict Voriconazole Clearance in Healthy Adults
por: Muhareb, Amin, et al.
Publicado: (2023)

Frailty as a Marker for the Plasma Concentrations of Direct Oral Anticoagulants in Older Patients: Results of an Exploratory Study
por: Eidam, Annette, et al.
Publicado: (2023)

Evaluation of CYP2C19 activity using microdosed oral omeprazole in humans
por: Elbe, Annika, et al.
Publicado: (2022)

Perpetrator Characteristics of Azole Antifungal Drugs on Three Oral Factor Xa Inhibitors Administered as a Microdosed Cocktail
por: Rohr, Brit Silja, et al.
Publicado: (2021)

Evaluation of the drug-drug interaction potential of the novel hepatitis B and D virus entry inhibitor bulevirtide at OATP1B in healthy volunteers
por: Zhu, Vanessa, et al.
Publicado: (2023)

Oral bioavailability of microdoses and therapeutic doses of midazolam as a 2-dimensionally printed orodispersible film in healthy volunteers
por: Breithaupt, Mareile H., et al.
Publicado: (2022)

Intact plasma quantification of the large therapeutic lipopeptide bulevirtide
por: Sauter, Max, et al.
Publicado: (2021)

Pharmacoenhancement of Low Crizotinib Plasma Concentrations in Patients with Anaplastic Lymphoma Kinase‐Positive Non‐Small Cell Lung Cancer using the CYP3A Inhibitor Cobicistat
por: Hohmann, Nicolas, et al.
Publicado: (2020)

Application of a microdosed cocktail of 3 oral factor Xa inhibitors to study drug–drug interactions with different perpetrator drugs
por: Mikus, Gerd, et al.
Publicado: (2020)

Pharmacokinetics of Pantoprazole and Pantoprazole Sulfone in Goats After Intravenous Administration: A Preliminary Report
por: Smith, Joe S., et al.
Publicado: (2021)

Environmentally Benign and Facile Process for the Synthesis of Pantoprazole Sodium Sesquihydrate: Phase Transformation of Pantoprazole Sodium Heterosolvate to Pantoprazole Sodium Sesquihydrate
por: Awasthi, Arun Kumar, et al.
Publicado: (2017)

Unexpected excessive apixaban exposure: case report of a patient with polymorphisms of multiple apixaban elimination pathways
por: Huppertz, Andrea, et al.
Publicado: (2019)

Drug–Drug Interactions with Direct Oral Anticoagulants
por: Foerster, Kathrin I., et al.
Publicado: (2020)

Correction to: Drug–Drug Interactions with Direct Oral Anticoagulants
por: Foerster, Kathrin I., et al.
Publicado: (2020)

Pantoprazole-related Symptomatic Hyponatremia
por: Ferreira, Filipa, et al.
Publicado: (2016)

Bioequivalence Study of Pantoprazole Sodium-HPBCD and Conventional Pantoprazole Sodium Enteric-Coated Tablet Formulations
por: Kamdi, Sandesh P., et al.
Publicado: (2013)

Low Exposure to Direct Oral Anticoagulants Is Associated with Ischemic Stroke and Its Severity
por: Rizos, Timolaos, et al.
Publicado: (2022)

Pharmacokinetic and pharmacodynamic properties of pantoprazole in calves
por: Olivarez, Jeff D., et al.
Publicado: (2023)

Quantification of the Time Course of CYP3A Inhibition, Activation, and Induction Using a Population Pharmacokinetic Model of Microdosed Midazolam Continuous Infusion
por: Nassar, Yomna M., et al.
Publicado: (2022)

Metabolic Effect of Blocking Sodium-Taurocholate Co-Transporting Polypeptide in Hypercholesterolemic Humans with a Twelve-Week Course of Bulevirtide—An Exploratory Phase I Clinical Trial
por: Stoll, Felicitas, et al.
Publicado: (2022)

The comparison of extemporaneous preparations of omeprazole, pantoprazole oral suspension and intravenous pantoprazole on the gastric pH of critically ill-patients
por: Dabiri, Yasamin, et al.
Publicado: (2015)

First‐in‐human, randomized, double‐blind, placebo‐controlled, dose escalation trial of the anti‐herpes simplex virus monoclonal antibody HDIT101 in healthy volunteers
por: Blank, Antje, et al.
Publicado: (2022)

Development and Validation of an LC–MS-Based Quantification Assay for New Therapeutic Antibodies: Application to a Novel Therapy against Herpes Simplex Virus
por: Fresnais, Margaux, et al.
Publicado: (2020)

Long-term management of GERD in the elderly with pantoprazole
por: Calabrese, Carlo, et al.
Publicado: (2007)

Effect of food on the pharmacokinetics of omeprazole, pantoprazole and rabeprazole
por: Ochoa, Dolores, et al.
Publicado: (2020)

Pantoprazole/tozinameran: Rowell's syndrome: case report
Publicado: (2021)

Pantoprazole impairs fracture healing in aged mice
por: Menger, Maximilian M., et al.
Publicado: (2020)

Anaphylaxis Caused by Taking Pantoprazole: Case Series
por: Telaku, Skender, et al.
Publicado: (2023)

An update on the use of pantoprazole as a treatment for gastroesophageal reflux disease
por: Mathews, Sony, et al.
Publicado: (2010)

Diclofenac- and Pantoprazole-Induced Rhabdomyolysis: A Potential Drug Interaction
por: Ertekin, Yusuf Haydar, et al.
Publicado: (2015)

Pantoprazole-Induced Delirium: Review of a Case and Associated Literature
por: Razdan, Anupriya, et al.
Publicado: (2018)

Pantoprazole-induced acute kidney injury: A case report
por: Peng, Tao, et al.
Publicado: (2018)

Pantoprazole-Associated Thrombocytopenia: A Literature Review and Case Report
por: Phan, Alexander T, et al.
Publicado: (2022)

Anaphylaxis as a Rare Side Effect of Pantoprazole; a Case Report
por: Faridaalaee, Gholamreza, et al.
Publicado: (2018)

Utility of the (13)C‐pantoprazole breath test as a CYP2C19 phenotyping probe for children
por: Feldman, Keith, et al.
Publicado: (2022)

A retrospective analysis of clinical outcomes between hospitalized patients with COVID‐19 who received famotidine or pantoprazole
por: Wagner, Justin J., et al.
Publicado: (2023)

Omeprazole-induced and pantoprazole-induced asymptomatic hyponatremia: a case report
por: van der Zalm, Isabel J. B., et al.
Publicado: (2020)

Long-term management of gastroesophageal reflux disease with pantoprazole
por: Scholten, Theo
Publicado: (2007)

Effect of pantoprazole and its interactions with vecuronium on the neuromuscular junction
por: Patel, Tejas K., et al.
Publicado: (2010)

Pantoprazole for the Treatment of Peptic Ulcer Bleeding and Prevention of Rebleeding
por: van Rensburg, Christo J., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_mf6hbab96gu34q7hapet51fqd0