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Screening of the whole human cytochrome P450 complement (CYPome) with enzyme bag cocktails
We have previously introduced the use of permeabilized fission yeast cells (enzyme bags) that recombinantly express full-length CYPs for drug metabolism studies. Such enzyme bags are cells with pores that function as enzymes in situ. They can easily be prepared without a need for ultracentrifugation...
Autores principales: | Sharma, Sangeeta Shrestha, Sharma, Shishir, Bureik, Matthias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Xi'an Jiaotong University
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322738/ https://www.ncbi.nlm.nih.gov/pubmed/32612874 http://dx.doi.org/10.1016/j.jpha.2020.05.003 |
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