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Current LC-MS-based strategies for characterization and quantification of antibody-drug conjugates

The past few years have witnessed enormous progresses in the development of antibody-drug conjugates (ADCs). Consequently, comprehensive analysis of ADCs in biological systems is critical in supporting discovery, development and evaluation of these agents. Liquid chromatography-mass spectrometry (LC...

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Detalles Bibliográficos
Autores principales: Zhu, Xiaoyu, Huo, Shihan, Xue, Chao, An, Bo, Qu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322744/
https://www.ncbi.nlm.nih.gov/pubmed/32612867
http://dx.doi.org/10.1016/j.jpha.2020.05.008