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Current status and future directions of high-throughput ADME screening in drug discovery

During the last decade high-throughput in vitro absorption, distribution, metabolism and excretion (HT-ADME) screening has become an essential part of any drug discovery effort of synthetic molecules. The conduct of HT-ADME screening has been “industrialized” due to the extensive development of soft...

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Detalles Bibliográficos
Autor principal: Shou, Wilson Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322755/
https://www.ncbi.nlm.nih.gov/pubmed/32612866
http://dx.doi.org/10.1016/j.jpha.2020.05.004