A humanized mouse model to study mast cells mediated cutaneous adverse drug reactions

Recently a G‐protein‐coupled receptor, MAS Related GPR Family Member X2 (MRGPRX2), was identified as a specific receptor on human mast cells responsible for IgE independent adverse drug reactions (ADR). Although a murine homologue, Mrgprb2, has been identified for this receptor, its affinity for man...

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Detalles Bibliográficos
Autores principales: Mencarelli, Andrea, Gunawan, Merry, Yong, Kylie Su Mei, Bist, Pradeep, Tan, Wilson Wei Sheng, Tan, Sue Yee, Liu, Min, Huang, Edwin Kunxiang, Fan, Yong, Chan, Jerry Kok Yen, Choi, Hae Woong, Abraham, Soman N., Chen, Qingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
11th Singapore Society for Immunology Annual Symposium
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322799/
https://www.ncbi.nlm.nih.gov/pubmed/31922289
http://dx.doi.org/10.1002/JLB.3MA1219-210RR

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