Cargando…

Exosomal circSHKBP1 promotes gastric cancer progression via regulating the miR-582-3p/HUR/VEGF axis and suppressing HSP90 degradation

BACKGROUND: Circular RNAs (circRNAs) play important regulatory roles in the development of various cancers. However, biological functions and the underlying molecular mechanism of circRNAs in gastric cancer (GC) remain obscure. METHODS: Differentially expressed circRNAs were identified by RNA sequen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xie, Mengyan, Yu, Tao, Jing, Xinming, Ma, Ling, Fan, Yu, Yang, Fengming, Ma, Pei, Jiang, Huning, Wu, Xi, Shu, Yongqian, Xu, Tongpeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322843/ https://www.ncbi.nlm.nih.gov/pubmed/32600329 http://dx.doi.org/10.1186/s12943-020-01208-3

Ejemplares similares

Exosomal circSHKBP1 participates in non-small cell lung cancer progression through PKM2-mediated glycolysis
por: Chen, Wenbiao, et al.
Publicado: (2022)

Circular RNA CircSHKBP1 accelerates the proliferation, invasion, angiogenesis, and stem cell-like properties via modulation of microR-766-5p/high mobility group AT-hook 2 axis in laryngeal squamous cell carcinoma
por: Chen, Fu, et al.
Publicado: (2022)

Silencing of circRACGAP1 sensitizes gastric cancer cells to apatinib via modulating autophagy by targeting miR-3657 and ATG7
por: Ma, Ling, et al.
Publicado: (2020)

CircRNAs in cancer metabolism: a review
por: Yu, Tao, et al.
Publicado: (2019)

Loss of miR-26b-5p promotes gastric cancer progression via miR-26b-5p-PDE4B/CDK8-STAT3 feedback loop
por: Xu, Tingting, et al.
Publicado: (2023)

circ-SHKBP1 Regulates the Angiogenesis of U87 Glioma-Exposed Endothelial Cells through miR-544a/FOXP1 and miR-379/FOXP2 Pathways
por: He, Qianru, et al.
Publicado: (2017)

Potential Regulatory Roles of MicroRNAs and Long Noncoding RNAs in Anticancer Therapies
por: Xie, Mengyan, et al.
Publicado: (2018)

Circ-HuR suppresses HuR expression and gastric cancer progression by inhibiting CNBP transactivation
por: Yang, Feng, et al.
Publicado: (2019)

LINC00675 Suppresses Cell Proliferation and Migration via Downregulating the H3K4me2 Level at the SPRY4 Promoter in Gastric Cancer
por: Pan, Yutian, et al.
Publicado: (2020)

Targeting IL8 as a sequential therapy strategy to overcome chemotherapy resistance in advanced gastric cancer
por: Jiang, Huning, et al.
Publicado: (2022)

Correction: Circ-HuR suppresses HuR expression and gastric cancer progression by inhibiting CNBP transactivation
por: Yang, Feng, et al.
Publicado: (2023)

Role of hypoxia in cancer therapy by regulating the tumor microenvironment
por: Jing, Xinming, et al.
Publicado: (2019)

Methylomic Analysis Identifies Frequent DNA Methylation of Zinc Finger Protein 582 (ZNF582) in Cervical Neoplasms
por: Huang, Rui-Lan, et al.
Publicado: (2012)

Exosome‐transmitted miR‐769‐5p confers cisplatin resistance and progression in gastric cancer by targeting CASP9 and promoting the ubiquitination degradation of p53
por: Jing, Xinming, et al.
Publicado: (2022)

Differential expression of angiogenesis markers HSP70, HSP90, VEGF and pERK1/2 in both components of dedifferentiated chondrosarcomas
por: Schoedel, Karen, et al.
Publicado: (2021)

Association between VEGF Gene Polymorphisms and the Susceptibility to Lung Cancer: An Updated Meta-Analysis
por: Yang, Fengming, et al.
Publicado: (2018)

Circulating heat shock protein 90 (Hsp90) and autoantibodies to Hsp90 are increased in patients with atopic dermatitis
por: Sitko, Krzysztof, et al.
Publicado: (2021)

Y‐632 inhibits heat shock protein 90 (Hsp90) function by disrupting the interaction between Hsp90 and Hsp70/Hsp90 organizing protein, and exerts antitumor activity in vitro and in vivo
por: Wang, Wenqian, et al.
Publicado: (2016)

JWA down-regulates HER2 expression via c-Cbl and induces lapatinib resistance in human gastric cancer cells
por: Ma, Ling, et al.
Publicado: (2016)

Hsp-90 and the biology of nematodes
por: Him, Nik AIIN, et al.
Publicado: (2009)

Mechanisms of Hsp90 regulation
por: Prodromou, Chrisostomos
Publicado: (2016)

Regulatory Mechanisms of Hsp90
por: Prodromou, Chrisostomos
Publicado: (2017)

Inhibitors of HSP90 in melanoma
por: Mielczarek-Lewandowska, Aleksandra, et al.
Publicado: (2019)

Role of HSP90 in Cancer
por: Birbo, Bereket, et al.
Publicado: (2021)

Organismal Roles of Hsp90
por: van Oosten-Hawle, Patricija
Publicado: (2023)

The Distinct Assignments for Hsp90α and Hsp90β: More Than Skin Deep
por: Chang, Cheng, et al.
Publicado: (2023)

Traditional and Novel Mechanisms of Heat Shock Protein 90 (HSP90) Inhibition in Cancer Chemotherapy Including HSP90 Cleavage
por: Park, Sangkyu, et al.
Publicado: (2019)

Hsp90 inhibitor HSP990 in very low dose upregulates EAAT2 and exerts potent antiepileptic activity
por: Sha, Longze, et al.
Publicado: (2020)

Circular RNA circStag1 promotes bone regeneration by interacting with HuR
por: Chen, Gaoyang, et al.
Publicado: (2022)

HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction and identify a noncanonical model of HSP90-mediated HSF1 regulation
por: Kijima, Toshiki, et al.
Publicado: (2018)

The Hsp70/Hsp90 Chaperone Machinery in Neurodegenerative Diseases
por: Lackie, Rachel E., et al.
Publicado: (2017)

CD24 promoted cancer cell angiogenesis via Hsp90-mediated STAT3/VEGF signaling pathway in colorectal cancer
por: Wang, Xinying, et al.
Publicado: (2016)

Targeting the Hsp90-Cdc37-client protein interaction to disrupt Hsp90 chaperone machinery
por: Li, Ting, et al.
Publicado: (2018)

582 Chronic Urticaria Associated with Thyroid Disease
por: de Guadalupe Peñaloza-González, Flor, et al.
Publicado: (2012)

Hsp40s Specify Functions of Hsp104 and Hsp90 Protein Chaperone Machines
por: Reidy, Michael, et al.
Publicado: (2014)

The Role of HSP90 Inhibitors in the Treatment of Cardiovascular Diseases
por: Qi, Shiyu, et al.
Publicado: (2022)

HSP90 inhibitor AUY922 induces cell death by disruption of the Bcr-Abl, Jak2 and HSP90 signaling network complex in leukemia cells
por: Tao, Wenjing, et al.
Publicado: (2015)

Control of Canalization and Evolvability by Hsp90
por: Milton, Claire C., et al.
Publicado: (2006)

Targeting HSP90 for cancer therapy
por: Mahalingam, D, et al.
Publicado: (2009)

Hsp90 depletion goes wild
por: Siegal, Mark L, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_ubkm5051070fnvqg3n72364fkt