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PRKCQ inhibition enhances chemosensitivity of triple-negative breast cancer by regulating Bim

BACKGROUND: Protein kinase C theta, (PRKCQ/PKCθ) is a serine/threonine kinase that is highly expressed in a subset of triple-negative breast cancers (TNBC) and promotes their growth, anoikis resistance, epithelial-mesenchymal transition (EMT), and invasion. Here, we show that PRKCQ regulates the sen...

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Detalles Bibliográficos
Autores principales:	Byerly, Jessica H., Port, Elisa R., Irie, Hanna Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322866/ https://www.ncbi.nlm.nih.gov/pubmed/32600444 http://dx.doi.org/10.1186/s13058-020-01302-w

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