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The evolutionarily conserved ESRE stress response network is activated by ROS and mitochondrial damage
BACKGROUND: Mitochondrial dysfunction causes or contributes to a wide variety of pathologies, including neurodegenerative diseases, cancer, metabolic diseases, and aging. Cells actively surveil a number of mitochondrial readouts to ensure that cellular homeostasis is maintained. RESULTS: In this art...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322875/ https://www.ncbi.nlm.nih.gov/pubmed/32600387 http://dx.doi.org/10.1186/s12915-020-00812-5 |