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Integration of genomics, metagenomics, and metabolomics to identify interplay between susceptibility alleles and microbiota in adenoma initiation

BACKGROUND: Colorectal cancer (CRC) is a multifactorial disease resulting from both genetic predisposition and environmental factors including the gut microbiota (GM), but deciphering the influence of genetic variants, environmental variables, and interactions with the GM is exceedingly difficult. W...

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Detalles Bibliográficos
Autores principales: Moskowitz, Jacob E., Doran, Anthony G., Lei, Zhentian, Busi, Susheel B., Hart, Marcia L., Franklin, Craig L., Sumner, Lloyd W., Keane, Thomas M., Amos-Landgraf, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322931/
https://www.ncbi.nlm.nih.gov/pubmed/32600361
http://dx.doi.org/10.1186/s12885-020-07007-9