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Integration of genomics, metagenomics, and metabolomics to identify interplay between susceptibility alleles and microbiota in adenoma initiation
BACKGROUND: Colorectal cancer (CRC) is a multifactorial disease resulting from both genetic predisposition and environmental factors including the gut microbiota (GM), but deciphering the influence of genetic variants, environmental variables, and interactions with the GM is exceedingly difficult. W...
Autores principales: | Moskowitz, Jacob E., Doran, Anthony G., Lei, Zhentian, Busi, Susheel B., Hart, Marcia L., Franklin, Craig L., Sumner, Lloyd W., Keane, Thomas M., Amos-Landgraf, James M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322931/ https://www.ncbi.nlm.nih.gov/pubmed/32600361 http://dx.doi.org/10.1186/s12885-020-07007-9 |
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